Sandisk (SNDK) has had the highest return between 2025 and 2026 by a mega-cap US stock, returning 4,931.9%.

ASSET	YEARS	% RETURN
Sandisk (SNDK)	2025-2026	4,931.86%
Micron Technology (MU)	2025-2026	1,114.09%
Seagate Technology (STX)	2025-2026	938.11%
Intel (INTC)	2025-2026	425.16%
Dell Technologies (DELL)	2025-2026	377.16%
Lam Research (LRCX)	2025-2026	339.2%
Advanced Micro Devices (AMD)	2025-2026	326.11%
Banco Santander SA ADR (SAN)	2025-2026	241.32%
KLA (KLAC)	2025-2026	191.73%
Applied Materials (AMAT)	2025-2026	188.95%
GE Vernova LLC (GEV)	2025-2026	186.77%
ASML Holding NV ADR (ASML)	2025-2026	148.74%
Crowdstrike (CRWD)	2025-2026	139.87%
HSBC Holdings PLC ADR (HSBC)	2025-2026	136.1%
Amphenol (APH)	2025-2026	134.5%
Caterpillar (CAT)	2025-2026	127.92%
Taiwan Semiconductor Manufacturing (TSM)	2025-2026	124.44%
Palantir Technologies (PLTR)	2025-2026	122.48%
Marvell Technology (MRVL)	2025-2026	113.37%
Arm Holdings plc American Depositary Shares (ARM)	2025-2026	111.39%
Mitsubishi UFJ Financial Group Inc ADR (MUFG)	2025-2026	106.48%
BHP (BHP)	2025-2026	103.52%
Citigroup (C)	2025-2026	102.65%
GE Aerospace (GE)	2025-2026	95.43%
Johnson & Johnson (JNJ)	2025-2026	92.6%

Mega-cap stocks are treated as having a market cap of $200B+.