ProKidney (PROK) had the highest return in July 2025 by a small-cap US stock, returning 377.6%.

ASSET	MONTH	% RETURN
ProKidney (PROK)	July 2025	377.59%
Newegg Commerce (NEGG)	July 2025	295.47%
Currenc Group Inc Ordinary Shares (CURR)	July 2025	130.77%
Stewards Inc Common Stock (SWRD)	July 2025	129.15%
SuperX AI Technology (SUPX)	July 2025	118.33%
Artiva Biotherapeutics, Inc Common Stock (ARTV)	July 2025	97.37%
Forward Industries (FWDI)	July 2025	97.23%
Lightwave Logic (LWLG)	July 2025	90.98%
Sharplink Gaming (SBET)	July 2025	88.67%
Ambiq Micro (AMBQ)	July 2025	82.71%
Oncology Institute (STLN)	July 2025	76.44%
Galectin Therapeutics (GALT)	July 2025	72.51%
XMax (XMAX)	July 2025	69.63%
Cellectis (CLLS)	July 2025	66.23%
Amprius Technologies (AMPX)	July 2025	64.61%
Energy Vault (NRGV)	July 2025	59.72%
Ramaco Resources (METCB)	July 2025	59.02%
Avalo Therapeutics (AVTX)	July 2025	58.43%
American Superconductor (AMSC)	July 2025	57.74%
Inhibrx Biosciences (INBX)	July 2025	55.02%
Prime Medicine, Inc Common Stock (PRME)	July 2025	53.91%
Ovid Therapeutics (OVID)	July 2025	53.37%
Compass Pathways (CMPS)	July 2025	53.17%
Betterware de México, SAPI de CV (BWMX)	July 2025	51.85%
HUYA (HUYA)	July 2025	51.36%

Small-cap stocks are treated as having a market cap between $300M and $2B.