TSS, Inc Common Stock (TSSI) had the highest return in March 2016 by a small-cap US stock, returning 700%.

ASSET	MONTH	% RETURN
TSS, Inc Common Stock (TSSI)	March 2016	700%
Vericel Corp Ord (VCEL)	March 2016	183.09%
Lsb Industries (LXU)	March 2016	113.92%
Platinum Group Metals (PLG)	March 2016	94.87%
Yirendai (YRD)	March 2016	92.72%
Baytex Energy (BTE)	March 2016	71.13%
Ryerson (RYI)	March 2016	71.08%
Metalla Royalty & Streaming (MTA)	March 2016	66.96%
Silvercorp Metals (SVM)	March 2016	65.53%
CorMedix (CRMD)	March 2016	64.6%
Village Farms International (VFF)	March 2016	64.09%
Olympic Steel (ZEUS)	March 2016	59.69%
Taseko Mines (TGB)	March 2016	56.75%
MannKind (MNKD)	March 2016	56.31%
Vital Energy (VTLE)	March 2016	55.49%
Americas Silver (USAS)	March 2016	55.37%
BlueLinx (BXC)	March 2016	52.5%
GoldMining (GLDG)	March 2016	50.3%
Western Copper and Gold (WRN)	March 2016	50.3%
eXp World (EXPI)	March 2016	45.35%
Orion (ORN)	March 2016	42.7%
3D Systems (DDD)	March 2016	42.58%
Arcos Dorados (ARCO)	March 2016	42.58%
Verastem (VSTM)	March 2016	41.07%
BioCryst Pharmaceuticals (BCRX)	March 2016	40.8%

Small-cap stocks are treated as having a market cap between $300M and $2B.