InterContinental Hotels Group PLC ADR (IHG) had the highest return between 2000 and 2007 by a US stock, returning 11,160,200%.

ASSET	YEARS	% RETURN
InterContinental Hotels Group PLC ADR (IHG)	2000-2007	11,160,200%
India Globalization Capital (IGC)	2000-2007	9,833,233.33%
Hirequest (HQI)	2000-2007	9,080,600%
Natwest (NWG)	2000-2007	9,034,940%
Northern Oil & Gas (NOG)	2000-2007	2,241,830.77%
Taoping (TAOP)	2000-2007	2,040,036.01%
National Grid PLC ADR (NGG)	2000-2007	1,604,552.94%
Cemtrex (CETX)	2000-2007	992,664.51%
Houston American Energy (HUSA)	2000-2007	762,273.18%
Perspective Therapeutics (CATX)	2000-2007	669,900%
Alto Ingredients (ALTO)	2000-2007	603,154.02%
Inseego (INSG)	2000-2007	269,900%
Ring Energy (REI)	2000-2007	263,900%
Ocean Power Technologies (OPTT)	2000-2007	180,233.33%
NextTrip (NTRP)	2000-2007	159,900%
Lixte Biotechnology (LIXT)	2000-2007	73,670.49%
ImmunoPrecise Antibodies (HYFT)	2000-2007	42,757.14%
First Majestic Silver (AG)	2000-2007	20,286.22%
Gyre Therapeutics (GYRE)	2000-2007	17,414.09%
Broadwind Energy (BWEN)	2000-2007	17,060.69%
Cryoport (CYRX)	2000-2007	15,727.03%
Americas Silver (USAS)	2000-2007	11,189.47%
Insmed (INSM)	2000-2007	10,693.24%
Companhia Siderurgica Nacional ADR (SID)	2000-2007	9,962.5%
Gladstone Capital (GLAD)	2000-2007	9,927.84%