InterContinental Hotels Group PLC ADR (IHG) had the highest return between 1999 and 2007 by a US stock, returning 11,160,200%.

ASSET	YEARS	% RETURN
InterContinental Hotels Group PLC ADR (IHG)	1999-2007	11,160,200%
India Globalization Capital (IGC)	1999-2007	9,833,233.33%
Hirequest (HQI)	1999-2007	9,080,600%
Natwest (NWG)	1999-2007	9,034,940%
Northern Oil & Gas (NOG)	1999-2007	2,241,830.77%
National Grid PLC ADR (NGG)	1999-2007	1,604,552.94%
Houston American Energy (HUSA)	1999-2007	789,452.39%
Know Labs (KNW)	1999-2007	763,220.61%
Perspective Therapeutics (CATX)	1999-2007	669,900%
Ring Energy (REI)	1999-2007	263,900%
Cemtrex (CETX)	1999-2007	259,910.33%
Ocean Power Technologies (OPTT)	1999-2007	180,233.33%
NextTrip (NTRP)	1999-2007	159,900%
ImmunoPrecise Antibodies (HYFT)	1999-2007	42,757.14%
Flexible Solutions International (FSI)	1999-2007	22,864.71%
First Majestic Silver (AG)	1999-2007	20,294.67%
Companhia Siderurgica Nacional ADR (SID)	1999-2007	17,821.53%
Gyre Therapeutics (GYRE)	1999-2007	17,414.09%
Broadwind Energy (BWEN)	1999-2007	17,060.69%
Cryoport (CYRX)	1999-2007	15,727.03%
OPTIMIZERx (OPRX)	1999-2007	11,900%
Versus Systems Inc. (VS)	1999-2007	10,020%
Deckers Outdoor (DECK)	1999-2007	7,194.16%
Monster Beverage (MNST)	1999-2007	6,502.5%
Gerdau SA ADR (GGB)	1999-2007	6,424.66%