Brera Holdings PLC Class B Ordinary Shares (BREA) had the highest return between 2020 and 2024 by a US stock with a market cap of $150+, returning 1,645,900%.

ASSET	YEARS	% RETURN
Brera Holdings PLC Class B Ordinary Shares (BREA)	2020-2024	1,645,900%
NioCorp Developments Ltd Common Stock (NB)	2020-2024	258,233.33%
MDxHealth SA ADR (MDXH)	2020-2024	215,354.55%
Integra Resources (ITRG)	2020-2024	144,900%
BioNexus Gene Lab Corp Common stock (BGLC)	2020-2024	68,192.68%
Applied Digital (APLD)	2020-2024	17,585.19%
Azitra (AZTR)	2020-2024	7,507.14%
Trump Media & Technology (DJTWW)	2020-2024	4,092.87%
Foremost Lithium Resource & Technology Ltd Common stock (FMST)	2020-2024	4,069.18%
Innodata (INOD)	2020-2024	3,366.67%
CPI Card (PMTS)	2020-2024	3,221.11%
Alpha Metallurgical Resources (AMR)	2020-2024	2,239.68%
Limbach (LMB)	2020-2024	2,199.46%
NVIDIA (NVDA)	2020-2024	2,159.34%
Zivo Bioscience (ZIVO)	2020-2024	2,071.72%
GameStop (GME)	2020-2024	1,941.69%
MicroStrategy (MSTR)	2020-2024	1,927.58%
Castellum (CTM)	2020-2024	1,769.16%
Build-A-Bear Workshop (BBW)	2020-2024	1,546.34%
Energy Services Of America (ESOA)	2020-2024	1,538.79%
Celsius (CELH)	2020-2024	1,536.02%
Byrna Technologies (BYRN)	2020-2024	1,416.32%
Modine Manufacturing (MOD)	2020-2024	1,384.38%
MicroCloud Hologram (HOLO)	2020-2024	1,329.16%
Tesla (TSLA)	2020-2024	1,327%