DarioHealth (DRIO) had the highest return between 2016 and 2022 by a US stock, returning 8,559,900%.

ASSET	YEARS	% RETURN
DarioHealth (DRIO)	2016-2022	8,559,900%
Amerant Bancorp (AMTB)	2016-2022	8,533,633.33%
Gogoro (GGR)	2016-2022	5,299,900%
BioNexus Gene Lab Corp Common stock (BGLC)	2016-2022	2,780,387.8%
KULR Technology (KULR)	2016-2022	2,399,900%
Freedom (FRHC)	2016-2022	1,353,853.49%
Weatherford International (WFRD)	2016-2022	876,363.16%
Diversified Energy (DEC)	2016-2022	579,200%
GreenPower Motor (GP)	2016-2022	540,525%
TNF Pharmaceuticals (TNFA)	2016-2022	264,470.57%
Immatics (IMTX)	2016-2022	174,100%
MDxHealth SA ADR (MDXH)	2016-2022	157,280.95%
MicroCloud Hologram (HOLO)	2016-2022	131,516.22%
Integra Resources (ITRG)	2016-2022	126,500%
Castellum (CTM)	2016-2022	46,566.67%
ImmunoPrecise Antibodies (HYFT)	2016-2022	34,633.33%
Metalla Royalty & Streaming (MTA)	2016-2022	14,059.71%
Applied Digital (APLD)	2016-2022	14,053.85%
Kaival Brands Innovations (KAVL)	2016-2022	12,365.28%
GeoVax Labs (GOVX)	2016-2022	12,334.21%
Avalon GloboCare (ALBT)	2016-2022	11,042.86%
AquaBounty Technologies (AQB)	2016-2022	10,511.11%
Aura Minerals Inc Common Shares (AUGO)	2016-2022	9,383.73%
ABOT (ABOT)	2016-2022	8,566.34%
Enphase Energy (ENPH)	2016-2022	7,624.78%