Xanadu Quantum Technologies Limited Class B Subordinate Voting Shares (XNDU) had the highest return on April 22 by a small-cap US stock, returning 29.1%.

ASSET	DATE	% RETURN
Xanadu Quantum Technologies Limited Class B Subordinate Voting Shares (XNDU)	4/22/2026	29.13%
Agencia Comercial Spirits Ltd Class A Ordinary Shares (AGCC)	4/22/2026	28.68%
Newsmax (NMAX)	4/22/2026	23.2%
Canopy Growth (CGC)	4/22/2026	20%
W&T Offshore (WTI)	4/22/2026	20%
FuelCell Energy (FCEL)	4/22/2026	18.12%
Replimune (REPL)	4/22/2026	17.01%
TJGC (TJGC)	4/22/2026	15.25%
Cybin (HELP)	4/22/2026	15.17%
Evolution Metals & Technologies Corp Common Stock (EMAT)	4/22/2026	14.55%
MapLight Therapeutics, Inc Common Stock (MPLT)	4/22/2026	14.1%
BRC (BRCC)	4/22/2026	13.68%
Fermi (FRMI)	4/22/2026	13.68%
agilon health (AGL)	4/22/2026	13.28%
Terrestrial Energy (IMSR)	4/22/2026	13.11%
Kelly Services B (KELYB)	4/22/2026	12.8%
Daqo New Energy Corp ADR (DQ)	4/22/2026	12.43%
Tilray (TLRY)	4/22/2026	12.35%
Falcon's Beyond Global, Inc Class A Common Stock (FBYD)	4/22/2026	10.95%
American Superconductor (AMSC)	4/22/2026	10.94%
Monarch Casino & Resort (MCRI)	4/22/2026	10.91%
POET Technologies (POET)	4/22/2026	10.75%
CoinShares PLC Ordinary Shares (CSHR)	4/22/2026	10.45%
Jade Biosciences (JBIO)	4/22/2026	10.3%
Lightwave Logic (LWLG)	4/22/2026	10.25%

Small-cap stocks are treated as having a market cap between $300M and $2B.