Indaptus Therapeutics (INDP) had the highest return on June 4 by a small-cap US stock, returning 122%.

ASSET	DATE	% RETURN
Indaptus Therapeutics (INDP)	6/4/2026	121.96%
Absci (ABSI)	6/4/2026	22.54%
Hyliion (HYLN)	6/4/2026	20.38%
First Tracks Biotherapeutics (TRAX)	6/4/2026	19.42%
Butterfly Network (BFLY)	6/4/2026	19.04%
LightPath Technologies (LPTH)	6/4/2026	18.41%
Alvotech (ALVO)	6/4/2026	18.35%
RoboStrategy, Inc Common Stock (BOT)	6/4/2026	15.95%
Unusual Machines (UMAC)	6/4/2026	15.36%
Energy Vault (NRGV)	6/4/2026	15.28%
Sunshine Silver Mining & Refining (SSMR)	6/4/2026	14.33%
Angel Studios (ANGX)	6/4/2026	14.07%
Generate Biomedicines, Inc Common Stock (GENB)	6/4/2026	13.87%
Evolent Health (EVH)	6/4/2026	13.77%
agilon health (AGL)	6/4/2026	13.56%
Bandwidth (BAND)	6/4/2026	13.32%
ProFrac (ACDC)	6/4/2026	13.2%
Beta Bionics, Inc Common Stock (BBNX)	6/4/2026	12.84%
Virgin Galactic (SPCE)	6/4/2026	12.38%
Artiva Biotherapeutics, Inc Common Stock (ARTV)	6/4/2026	12.28%
Personalis (PSNL)	6/4/2026	12.24%
ArriVent BioPharma, Inc Common Stock (AVBP)	6/4/2026	12.21%
Oncology Institute (STLN)	6/4/2026	11.79%
Intellia Therapeutics (NTLA)	6/4/2026	11.74%
P3 Health Partners (PIII)	6/4/2026	11.65%

Small-cap stocks are treated as having a market cap between $300M and $2B.