Integra Resources (ITRG) has had the highest return between 2019 and 2102 by a US stock, returning 979,900%.

ASSET	YEARS	% RETURN
Integra Resources (ITRG)	2019-2102	979,900%
Applied Digital (APLD)	2019-2102	271,972.07%
MDxHealth SA ADR (MDXH)	2019-2102	194,605.88%
Sapiens International (SPNS)	2019-2102	144,470.07%
DevvStream Corp Common Stock (DEVS)	2019-2102	140,900%
BioNexus Gene Lab Corp Common stock (BGLC)	2019-2102	99,168.29%
Fubotv (FUBO)	2019-2102	34,557.53%
FitLife Brands, Inc Common Stock (FTLF)	2019-2102	31,380%
Centrus Energy (LEU)	2019-2102	18,217.68%
Weatherford International (WFRD)	2019-2102	16,969.93%
GeoVax Labs (GOVX)	2019-2102	11,775%
Heart Test Laboratories Inc Common Stock (HSCS)	2019-2102	8,958.82%
Regencell Bioscience (RGC)	2019-2102	8,462.38%
Castellum (CTM)	2019-2102	6,871.83%
LMF Acquisition Opportunities (ICU)	2019-2102	6,507.14%
Moolec Science SA Ordinary Shares (MLEC)	2019-2102	6,474.92%
Teekay Tankers (TNK)	2019-2102	6,093.09%
Axsome Therapeutics (AXSM)	2019-2102	6,002.85%
NVIDIA (NVDA)	2019-2102	5,708.14%
Azitra (AZTR)	2019-2102	4,966.07%
Foremost Lithium Resource & Technology Ltd Common stock (FMST)	2019-2102	4,828.72%
Aura Minerals Inc Common Shares (AUGO)	2019-2102	4,714.47%
Celsius (CELH)	2019-2102	4,155.75%
Innodata (INOD)	2019-2102	4,118.37%
QMMM Holdings Limited Ordinary Shares (QMMM)	2019-2102	3,880%