GeoVax Labs (GOVX) had the highest return between 2008 and 2015 by a US stock, returning 5,263,157,794.2%.

ASSET	YEARS	% RETURN
GeoVax Labs (GOVX)	2008-2015	5,263,157,794.21%
LM Funding America (LMFA)	2008-2015	8,979,697.98%
Future Fintech (FTFT)	2008-2015	6,974,258.97%
Sequans Communications (SQNS)	2008-2015	2,530,020.48%
QXO (QXO)	2008-2015	1,363,877.78%
Aurora Cannabis (ACB)	2008-2015	646,380%
Processa Pharmaceuticals (PCSA)	2008-2015	466,566.67%
TCTM Kids IT Education (VSA)	2008-2015	328,228.9%
Akari Therapeutics (AKTX)	2008-2015	231,900%
Versus Systems Inc. (VS)	2008-2015	111,260%
Prairie Operating Co Common Stock (PROP)	2008-2015	43,378.26%
Anfield Energy (AEC)	2008-2015	42,621.52%
Nutex Health (NUTX)	2008-2015	29,900%
Eastside Distilling (BLNE)	2008-2015	16,116.22%
Cementos Pacasmayo SAA ADR (CPAC)	2008-2015	11,241.95%
Pioneer Power Solutions (PPSI)	2008-2015	7,807.69%
Arena (AREN)	2008-2015	7,012.07%
Oxley Bridge Acquisition Limited Class A Ordinary Shares (OBA)	2008-2015	5,191.19%
Metalla Royalty & Streaming (MTA)	2008-2015	4,828.57%
FiEE (FIEE)	2008-2015	4,540%
Par Pacific (PARR)	2008-2015	3,823.33%
Avita Medical (RCEL)	2008-2015	3,635.49%
GT Biopharma (GTBP)	2008-2015	3,455.56%
Netflix (NFLX)	2008-2015	2,914.76%
Intellinetics (INLX)	2008-2015	2,900%