Centene (CNC) had the lowest return in July 2025 by a large-cap US stock, returning -52%.

ASSET	MONTH	% RETURN
Centene (CNC)	July 2025	-52.01%
Molina Healthcare (MOH)	July 2025	-46.76%
Charter Communications (CHTR)	July 2025	-33.95%
Align Technology (ALGN)	July 2025	-31.4%
Novo Nordisk A-S (NVO)	July 2025	-31.19%
CoreWeave, Inc Class A Common Stock (CRWV)	July 2025	-29.89%
Baxter International (BAX)	July 2025	-27.61%
Elevance Health (ELV)	July 2025	-27.25%
Chipotle Mexican Grill (CMG)	July 2025	-23.66%
Guardant Health (GH)	July 2025	-20.77%
Fair Isaac (FICO)	July 2025	-20.47%
Teck Resources Ltd Class B (TECK)	July 2025	-20.34%
Nokia (NOK)	July 2025	-20.05%
UnitedHealth (UNH)	July 2025	-20.01%
Natera (NTRA)	July 2025	-19.87%
Cigna (CI)	July 2025	-19.44%
Spotify Technology (SPOT)	July 2025	-18.31%
Exelixis (EXEL)	July 2025	-17.85%
Brown & Brown (BRO)	July 2025	-17.67%
Waters (WAT)	July 2025	-16.98%
Anheuser Busch Inbev NV ADR (BUD)	July 2025	-16.71%
Gartner (IT)	July 2025	-16.08%
Check Point Software Technologies (CHKP)	July 2025	-15.94%
Glaukos (GKOS)	July 2025	-15.83%
Royal Gold (RGLD)	July 2025	-15.59%

Large-cap stocks are treated as having a market cap of $10B+.