Scienture (SCNX) had the lowest return between 2009 and 2011 by a US stock, returning -99.9%.

ASSET	YEARS	% RETURN
Scienture (SCNX)	2009-2011	-99.89%
Xcel Brands (XELB)	2009-2011	-99.87%
Modular Medical (MODD)	2009-2011	-99.85%
TOMI Environmental Solutions (TOMZ)	2009-2011	-99.57%
Quantum Computing (QUBT)	2009-2011	-99.57%
Cayson Acquisition Corp Right (CAPNR)	2009-2011	-99.42%
Helport AI Limited Ordinary Shares (HPAI)	2009-2011	-99.12%
INVO Fertility (IVF)	2009-2011	-99.04%
Wetouch Technology Inc Common Stock (WETH)	2009-2011	-99%
BRC (RILY)	2009-2011	-98.7%
Ryvyl (RVYL)	2009-2011	-98.36%
Blink Charging (BLNK)	2009-2011	-98.19%
First BanCorp (FBP)	2009-2011	-97.83%
Applied Digital (APLD)	2009-2011	-97.6%
ABVC BioPharma (ABVC)	2009-2011	-97.42%
Seanergy Maritime (SHIP)	2009-2011	-97.28%
TherapeuticsMD (TXMD)	2009-2011	-97%
Riot Platforms (RIOT)	2009-2011	-96.93%
OptimumBank (OPHC)	2009-2011	-96.93%
Biocardia (BCDA)	2009-2011	-95.18%
SANUWAVE Health, Inc Common Stock (SNWV)	2009-2011	-95.05%
Recon Technology (RCON)	2009-2011	-95%
TG Therapeutics (TGTX)	2009-2011	-95%
Coda Octopus (CODA)	2009-2011	-95%
Microbot Medical (MBOT)	2009-2011	-94.1%