DeMar DeRozan had his most points in a game in 2021-22 against the Clippers on March 31, 2022, with 50 points.
| NAME | PTS | DATE | TM | OPP | MIN | REB | AST | STL | BLK | FGM | FGA | FG% | 3PM | 3PA | 3P% | FTM | FTA | FT% | TS% | OREB | DREB | TOV | PF | +/- | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. DeRozan | 50 | 3/31/2022 | vs | 43 | 5 | 6 | 1 | 0 | 17 | 26 | 65.4 | 2 | 2 | 100.0 | 14 | 15 | 93.3 | 76.7 | 0 | 5 | 2 | 4 | +19 | ||
| 2 | | D. DeRozan | 45 | 2/6/2022 | vs | 41 | 9 | 7 | 1 | 0 | 18 | 30 | 60.0 | 0 | 2 | 0.0 | 9 | 11 | 81.8 | 64.6 | 1 | 8 | 3 | 3 | -3 | ||
| 3 | | D. DeRozan | 41 | 1/23/2022 | @ | 38 | 5 | 3 | 2 | 0 | 15 | 21 | 71.4 | 0 | 0 | 11 | 13 | 84.6 | 76.7 | 2 | 3 | 3 | 3 | +3 | |||
| 4 | | D. DeRozan | 40 | 4/5/2022 | vs | 37 | 3 | 6 | 1 | 0 | 16 | 26 | 61.5 | 0 | 2 | 0.0 | 8 | 8 | 100.0 | 67.8 | 2 | 1 | 4 | 5 | -17 | ||
| 5 | | D. DeRozan | 40 | 2/14/2022 | vs | 35 | 3 | 7 | 0 | 0 | 16 | 24 | 66.7 | 0 | 0 | 8 | 8 | 100.0 | 72.7 | 0 | 3 | 3 | 1 | +15 | |||
| 6 | | D. DeRozan | 38 | 2/16/2022 | vs | 41 | 6 | 6 | 1 | 0 | 16 | 27 | 59.3 | 1 | 1 | 100.0 | 5 | 5 | 100.0 | 65.1 | 1 | 5 | 4 | 3 | +9 | ||
| 7 | | D. DeRozan | 38 | 2/12/2022 | vs | 40 | 6 | 5 | 1 | 0 | 12 | 24 | 50.0 | 0 | 1 | 0.0 | 14 | 16 | 87.5 | 61.2 | 1 | 5 | 2 | 2 | -4 | ||
| 8 | | D. DeRozan | 38 | 2/7/2022 | vs | 36 | 5 | 4 | 2 | 0 | 16 | 27 | 59.3 | 0 | 1 | 0.0 | 6 | 8 | 75.0 | 62.3 | 2 | 3 | 3 | 2 | -23 | ||
| 9 | | D. DeRozan | 38 | 12/19/2021 | vs | 34 | 4 | 6 | 1 | 0 | 11 | 24 | 45.8 | 0 | 0 | 16 | 17 | 94.1 | 60.4 | 1 | 3 | 3 | 2 | +6 | |||
| 10 | | D. DeRozan | 38 | 11/15/2021 | @ | 35 | 3 | 6 | 1 | 1 | 15 | 23 | 65.2 | 2 | 5 | 40.0 | 6 | 6 | 100.0 | 74.1 | 0 | 3 | 3 | 2 | +17 | ||
| 11 | | D. DeRozan | 37 | 3/28/2022 | @ | 41 | 6 | 7 | 0 | 0 | 12 | 26 | 46.2 | 1 | 1 | 100.0 | 12 | 12 | 100.0 | 59.1 | 0 | 6 | 4 | 4 | -8 | ||
| 12 | | D. DeRozan | 37 | 2/24/2022 | vs | 37 | 6 | 3 | 1 | 0 | 15 | 21 | 71.4 | 2 | 3 | 66.7 | 5 | 7 | 71.4 | 76.8 | 1 | 5 | 2 | 2 | +1 | ||
| 13 | | D. DeRozan | 37 | 11/3/2021 | @ | 36 | 10 | 1 | 1 | 0 | 13 | 22 | 59.1 | 0 | 1 | 0.0 | 11 | 12 | 91.7 | 67.8 | 2 | 8 | 3 | 2 | +12 | ||
| 14 | | D. DeRozan | 37 | 11/1/2021 | @ | 34 | 6 | 2 | 1 | 1 | 15 | 20 | 75.0 | 3 | 4 | 75.0 | 4 | 5 | 80.0 | 83.3 | 0 | 6 | 1 | 3 | +4 | ||
| 15 | | D. DeRozan | 36 | 3/9/2022 | @ | 41 | 8 | 4 | 2 | 0 | 12 | 25 | 48.0 | 0 | 1 | 0.0 | 12 | 13 | 92.3 | 58.6 | 0 | 8 | 2 | 0 | +8 | ||
| 16 | | D. DeRozan | 36 | 2/9/2022 | @ | 38 | 5 | 4 | 0 | 0 | 13 | 19 | 68.4 | 3 | 4 | 75.0 | 7 | 10 | 70.0 | 76.9 | 0 | 5 | 5 | 4 | -8 | ||
| 17 | | D. DeRozan | 35 | 2/11/2022 | vs | 38 | 6 | 6 | 1 | 0 | 14 | 22 | 63.6 | 0 | 1 | 0.0 | 7 | 7 | 100.0 | 69.8 | 0 | 6 | 0 | 1 | +19 | ||
| 18 | | D. DeRozan | 35 | 1/21/2022 | @ | 38 | 6 | 3 | 0 | 0 | 9 | 18 | 50.0 | 0 | 3 | 0.0 | 17 | 18 | 94.4 | 67.5 | 1 | 5 | 1 | 0 | +1 | ||
| 19 | | D. DeRozan | 35 | 12/27/2021 | @ | 38 | 5 | 10 | 0 | 0 | 14 | 20 | 70.0 | 2 | 2 | 100.0 | 5 | 8 | 62.5 | 74.4 | 1 | 4 | 3 | 3 | +7 | ||
| 20 | | D. DeRozan | 35 | 11/14/2021 | @ | 38 | 7 | 5 | 0 | 0 | 12 | 16 | 75.0 | 1 | 1 | 100.0 | 10 | 11 | 90.9 | 84.0 | 1 | 6 | 2 | 3 | +14 | ||
| 21 | | D. DeRozan | 34 | 12/2/2021 | @ | 38 | 6 | 3 | 1 | 1 | 12 | 19 | 63.2 | 0 | 0 | 10 | 11 | 90.9 | 71.3 | 0 | 6 | 2 | 4 | -3 | |||
| 22 | | D. DeRozan | 32 | 3/29/2022 | @ | 36 | 7 | 4 | 2 | 0 | 12 | 27 | 44.4 | 1 | 2 | 50.0 | 7 | 7 | 100.0 | 53.2 | 0 | 7 | 1 | 3 | +10 | ||
| 23 | | D. DeRozan | 32 | 1/28/2022 | @ | 37 | 6 | 8 | 0 | 0 | 13 | 22 | 59.1 | 1 | 1 | 100.0 | 5 | 5 | 100.0 | 66.1 | 0 | 6 | 1 | 1 | -6 | ||
| 24 | | D. DeRozan | 32 | 10/30/2021 | vs | 35 | 6 | 3 | 0 | 0 | 13 | 22 | 59.1 | 0 | 1 | 0.0 | 6 | 6 | 100.0 | 64.9 | 1 | 5 | 1 | 1 | +15 | ||
| 25 | | D. DeRozan | 31 | 2/26/2022 | vs | 42 | 7 | 3 | 2 | 1 | 10 | 29 | 34.5 | 2 | 2 | 100.0 | 9 | 10 | 90.0 | 46.4 | 1 | 6 | 1 | 2 | -1 | ||
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