The Los Angeles Lakers have the highest point differential by a team in the playoffs, with a 1,848 point differential.

highest point differential in nba playoff series sweep

TEAM	DIFF	GP	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	PTS	REB	AST	STL	BLK	TOV	PF
Lakers	1,848	782	241.4	104.0	48.0	22.9	7.7	5.7	39.2	85.5	45.8	4.8	14.3	33.8	22.6	30.8	73.4	52.5	12.5	30.5	14.6	188,805	81,308	36,492	17,936	3,947	2,936	7,489	18,768
Celtics	1,766	737	242.4	105.2	50.0	23.3	7.2	4.9	39.5	89.1	44.4	6.3	18.0	34.7	22.2	28.6	77.5	51.7	11.5	31.5	14.8	178,630	77,529	36,727	17,140	3,699	2,507	7,649	18,099
Spurs	726	403	241.7	99.8	42.7	21.6	7.2	5.4	37.5	81.2	46.2	5.6	15.5	36.4	19.4	26.3	73.6	53.8	11.5	31.2	14.1	97,395	40,210	17,192	8,724	2,901	2,196	5,696	8,967
Warriors	689	384	241.1	105.4	50.7	22.8	8.6	5.6	39.7	91.9	43.2	10.7	28.8	36.9	20.3	27.4	73.9	50.7	11.9	32.4	15.1	92,585	40,471	18,087	8,738	2,100	1,364	3,696	9,370
Bulls	363	349	242.2	97.6	43.2	21.8	7.8	4.7	37.1	82.6	44.9	4.7	13.9	33.9	19.6	26.0	75.4	51.9	13.1	29.1	14.2	84,535	34,079	15,070	7,613	2,488	1,497	4,516	8,216
Cavaliers	307	246	241.4	98.3	41.6	20.7	6.9	4.9	36.1	79.8	45.3	7.4	21.1	35.3	19.2	25.6	74.9	54.0	11.1	30.5	13.8	59,390	24,191	10,225	5,085	1,698	1,194	3,383	5,215
Heat	226	295	241.4	96.0	40.1	19.1	7.1	4.6	34.7	76.9	45.1	8.0	22.8	35.2	18.6	25.0	74.3	54.6	9.3	30.7	13.9	71,225	28,315	11,822	5,627	2,080	1,365	4,095	6,500
Bucks	208	312	242.1	104.5	44.4	23.4	7.5	5.0	40.1	86.0	46.7	6.1	18.0	33.8	19.5	26.0	75.0	53.6	11.9	31.2	15.0	75,530	32,595	13,838	7,289	2,041	1,350	4,066	7,410
Pistons	133	370	241.6	96.1	45.4	20.6	6.8	4.9	35.8	82.7	43.3	4.0	12.0	33.4	21.6	28.9	74.5	50.4	12.7	29.1	13.8	89,400	35,551	16,625	7,616	1,975	1,405	3,981	9,174
Packers	6	8	240.0	75.5		15.8			24.8	85.5	28.9				26.0	34.6	75.1	37.5				1,920	604		126				251
Red Skins	2	3	240.0	88.0		19.7			29.7	77.0	38.5				28.7	42.7	67.2	45.9				720	264		59				94
Pacers	1	258	241.5	94.8	40.6	20.3	6.9	4.6	34.2	76.8	44.5	6.5	18.2	35.8	19.8	26.0	76.4	53.7	10.9	29.8	14.6	62,295	24,457	10,483	5,226	1,791	1,182	3,776	6,081
Rebels	-8	3	240.0	74.0		7.7			28.0	89.3	31.3				18.0	24.7	73.0	36.9				720	222		23				67
Bullets	-13	16	241.6	77.8	51.5	9.2			25.4	84.6	30.0				27.0	37.1	72.7	38.5				3,865	1,244	103	147				485
Thunder	-17	341	242.2	101.6	43.6	20.9	7.8	5.4	37.9	83.8	45.2	5.9	17.4	33.9	20.8	27.0	76.9	53.1	13.2	30.3	15.0	82,590	34,638	14,852	7,117	2,649	1,857	5,112	8,250
Olympians	-50	13	240.0	80.4	39.7	18.9			28.5	78.2	36.5				23.3	32.1	72.7	43.6				3,120	1,045	278	246				342
Stags	-53	20	240.0	72.9		6.5			26.9	100.8	26.7				19.1	29.0	65.9	32.1				4,800	1,458		129				528
Suns	-55	324	242.0	106.0	42.5	23.7	7.4	5.2	40.1	85.7	46.8	5.9	16.3	36.0	20.6	26.7	77.2	54.4	11.8	30.3	14.6	78,410	34,340	13,760	7,669	2,347	1,644	4,614	7,566
Capitols	-55	19	241.3	73.5		11.0			24.9	85.5	29.2				23.6	32.7	72.3	36.8				4,585	1,397		209				531
76ers	-86	488	241.6	102.6	49.1	22.2	8.1	5.8	38.0	86.3	44.0	4.3	12.7	33.5	24.1	32.4	74.5	51.0	12.7	30.3	15.6	117,920	50,092	23,422	10,813	2,623	1,893	5,069	12,080
Bombers	-107	12	240.0	61.7		6.1			24.1	90.3	26.7				13.5	21.2	63.8	31.0				2,880	740		73				267
Magic	-113	140	241.6	95.9	40.2	19.2	6.6	4.7	34.4	76.8	44.8	8.1	23.2	34.8	19.0	26.9	70.5	54.1	10.8	29.4	14.1	33,825	13,420	5,633	2,685	920	655	1,972	3,145
Rockets	-142	322	241.6	102.0	42.8	22.0	7.7	5.3	37.9	83.4	45.4	7.0	20.3	34.3	19.8	26.7	74.3	53.6	12.2	30.6	14.8	77,780	32,833	13,797	7,087	2,448	1,676	4,686	7,336
Clippers	-162	153	241.0	104.6	41.8	21.3	7.4	4.7	38.9	83.8	46.4	8.7	24.3	35.8	19.4	26.0	74.5	54.9	10.4	31.4	13.8	36,870	15,999	6,395	3,255	1,138	724	2,110	3,577
Hornets	-182	63	243.6	92.9	40.4	20.1	7.5	4.6	34.2	78.2	43.7	4.4	13.3	33.0	20.1	26.8	75.0	51.6	11.7	28.7	14.0	15,345	5,853	2,545	1,266	471	292	880	1,407