Isaiah Thomas has his most career points per game versus the Wizards, with 21.3 per game.

isaiah thomas highest career ppg by opponent

OPP	PPG	GP	MPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
Wizards	21.3	16	30.7	3.4	6.3	1.0	0.1	2.5	6.9	16.3	42.5	1.8	5.4	33.7	5.6	6.4	87.4	492	341	54	100	16	1	40	30	+61
76ers	20.9	17	28.3	2.9	4.5	0.9	0.0	2.6	6.5	13.6	47.4	1.9	4.5	42.9	6.1	6.6	92.0	481	356	50	77	16	0	45	39	+110
Pistons	19.8	22	30.4	2.4	5.4	0.5	0.2	2.5	6.3	14.0	44.7	2.0	5.3	38.8	5.2	6.1	85.2	669	436	52	118	12	5	54	45	+29
Bucks	19.8	16	27.6	2.3	4.2	0.9	0.2	2.3	6.1	12.5	48.5	2.2	5.3	41.7	5.5	6.3	88.0	441	317	37	67	15	3	37	31	+62
Heat	19.5	20	31.2	2.6	4.9	0.8	0.1	2.4	6.2	15.2	40.6	2.7	6.5	40.8	4.6	5.3	85.8	624	390	51	98	16	1	48	42	-16
Knicks	19.3	19	27.8	3.0	4.7	0.8	0.1	1.2	5.7	14.4	39.8	1.9	5.9	31.9	5.9	6.7	89.0	528	367	57	89	16	2	22	25	+66
Hornets	19.1	18	29.2	2.8	5.6	0.4	0.1	2.4	6.4	14.6	44.3	2.3	6.3	37.2	3.8	4.7	81.2	526	343	51	101	7	2	43	46	+115
Raptors	19.1	18	29.8	2.1	5.1	0.9	0.1	2.2	6.1	14.0	43.3	2.3	6.1	37.6	4.7	5.3	88.4	536	343	38	91	16	1	40	35	-24
Grizzlies	18.6	17	30.7	2.5	5.1	0.9	0.1	2.2	5.8	13.9	41.4	1.8	5.8	31.6	5.2	5.8	90.8	522	316	43	86	16	1	37	30	-29
Suns	18.2	18	28.6	2.8	4.6	0.9	0.1	2.7	5.8	13.5	42.8	1.8	5.2	34.0	4.8	5.3	91.6	515	327	51	82	16	1	48	53	+79
Rockets	18.1	18	34.4	2.8	6.1	1.3	0.2	2.7	5.9	14.6	40.3	2.1	5.6	37.6	4.2	5.1	83.5	619	326	50	110	23	3	48	40	-66
Clippers	17.5	20	27.8	2.1	4.0	1.0	0.2	2.4	5.0	11.5	43.0	2.0	5.1	38.6	5.6	6.2	91.1	556	349	41	80	19	3	47	54	-38
Mavericks	17.4	18	28.3	2.1	4.9	0.6	0.0	1.9	5.8	13.5	42.8	1.9	5.8	32.4	4.0	4.6	86.7	510	314	37	88	11	0	34	37	+18
Pelicans	17.4	21	26.3	2.1	3.8	1.2	0.1	2.1	6.2	12.5	49.6	2.0	4.2	47.2	3.0	3.6	84.0	553	365	45	79	25	2	45	44	+86
Cavaliers	17.2	21	27.5	2.9	5.3	0.8	0.2	2.2	5.4	12.8	42.4	1.4	4.9	28.4	5.0	5.9	85.4	578	362	61	111	16	5	47	32	+24
Thunder	17.2	18	24.4	1.4	3.5	0.7	0.1	1.7	5.9	11.6	50.7	2.3	5.0	45.6	3.1	3.6	87.5	439	309	26	63	12	1	31	36	-80
Hawks	17.1	17	28.0	2.8	5.1	0.8	0.2	2.8	5.1	13.9	36.7	2.1	5.6	37.5	4.8	5.2	92.0	476	291	48	86	14	3	48	39	-73
Lakers	17.1	21	26.1	1.9	4.8	1.1	0.1	2.0	6.2	11.4	54.2	2.0	4.3	45.6	2.8	3.4	81.7	549	359	39	100	23	2	43	35	-6
Nets	16.7	16	26.2	2.5	4.7	0.8	0.2	2.3	5.6	13.7	41.1	1.6	5.9	27.7	3.8	4.3	89.7	420	267	40	75	12	3	37	31	+73
Pacers	16.5	17	27.2	2.0	4.2	0.7	0.2	2.7	5.1	13.6	37.7	1.8	5.5	31.9	4.5	5.1	89.5	462	281	34	71	12	4	46	38	+9
Spurs	16.3	21	28.2	2.0	4.7	0.7	0.0	2.2	5.6	13.4	41.8	1.4	5.0	27.4	3.7	4.2	88.6	592	343	42	98	15	1	46	47	-112
Bulls	16.2	18	27.2	2.1	3.1	0.7	0.1	2.1	5.4	11.7	46.0	2.0	4.8	41.4	3.4	4.3	78.2	489	291	37	56	13	1	38	29	+10
Nuggets	16.2	19	29.1	2.3	4.9	0.9	0.2	2.9	5.2	12.6	41.4	1.5	4.5	32.6	4.3	4.9	86.2	553	307	44	93	18	3	55	47	-39
Trail Blazers	16.1	20	25.8	2.1	4.1	0.6	0.1	1.8	5.5	13.6	40.4	1.6	4.8	33.3	3.5	4.3	81.4	517	322	42	82	12	1	36	35	+7
Jazz	16.0	20	27.0	2.1	5.0	0.9	0.1	1.9	5.6	11.4	49.3	1.5	3.6	41.7	3.3	3.7	89.2	541	320	42	100	18	1	38	38	-14