The Orlando Magic have the highest point differential by a team in a playoff game against the Cavaliers, with a 38 point differential in Game 3 of the 2024 First Round.

largest margin of victory in a game against the cavaliers postseason

TEAM	DIFF	DATE	TM		OPP	RESULT	MIN	PTS	REB	AST	STL	BLK	TOV	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	PF
Orlando Magic	38	4/25/2024	ORL	vs	CLE	W 121-83	240	121	51	24	7	3	8	47	92	51.1	13	37	35.1	14	16	87.5	21
Washington Wizards	36	4/24/2008	WAS	vs	CLE	W 108-72	240	108	36	20	13	5	11	38	73	52.1	8	19	42.1	24	33	72.7	17
Indiana Pacers	34	4/27/2018	IND	vs	CLE	W 121-87	240	121	45	27	9	1	7	49	87	56.3	15	30	50.0	8	14	57.1	18
Golden State Warriors	33	6/5/2016	GSW	vs	CLE	W 110-77	240	110	46	26	7	9	20	44	81	54.3	15	33	45.5	7	10	70.0	20
Boston Celtics	32	5/11/2010	BOS	@	CLE	W 120-88	240	120	41	25	6	4	10	44	80	55.0	8	15	53.3	24	34	70.6	28
Boston Celtics	31	5/15/1992	BOS	vs	CLE	W 122-91	240	122	44	41	11	6	9	52	88	59.1	0	6	0.0	18	22	81.8	17
Indiana Pacers	29	4/23/1998	IND	vs	CLE	W 106-77	240	106	33	24	12	9	10	34	67	50.7	8	17	47.1	30	41	73.2	25
Detroit Pistons	27	5/7/2006	DET	vs	CLE	W 113-86	240	113	40	23	4	9	10	42	81	51.9	15	22	68.2	14	18	77.8	19
Boston Celtics	25	5/13/2018	BOS	vs	CLE	W 108-83	240	108	48	27	6	4	9	43	84	51.2	11	30	36.7	11	13	84.6	17
New York Knicks	24	4/27/1995	NYK	vs	CLE	W 103-79	240	103	41	30	9	9	19	46	73	63.0	4	12	33.3	7	12	58.3	26
Orlando Magic	23	4/27/2024	ORL	vs	CLE	W 112-89	240	112	43	24	7	6	17	43	77	55.8	12	26	46.2	14	19	73.7	19
Golden State Warriors	23	6/8/2018	GSW	@	CLE	W 108-85	240	108	44	25	7	13	8	39	86	45.3	14	38	36.8	16	16	100.0	24
New York Knicks	23	4/25/1996	NYK	@	CLE	W 106-83	240	106	31	32	4	4	4	38	74	51.4	17	22	77.3	13	16	81.3	15
Chicago Bulls	23	5/27/1992	CHI	vs	CLE	W 112-89	240	112	52	20	13	7	9	43	85	50.6	1	2	50.0	25	35	71.4	24
Golden State Warriors	22	6/1/2017	GSW	vs	CLE	W 113-91	240	113	50	31	12	3	4	45	106	42.5	12	33	36.4	11	16	68.8	24
Golden State Warriors	21	6/11/2015	GSW	@	CLE	W 103-82	240	103	44	24	5	5	7	36	77	46.8	12	30	40.0	19	27	70.4	21
New York Knicks	20	4/21/2023	NYK	vs	CLE	W 99-79	240	99	45	21	14	5	14	39	83	47.0	10	33	30.3	11	18	61.1	17
Golden State Warriors	19	6/3/2018	GSW	vs	CLE	W 122-103	240	122	41	28	3	8	12	47	82	57.3	15	36	41.7	13	21	61.9	25
Golden State Warriors	19	6/4/2017	GSW	vs	CLE	W 132-113	240	132	53	34	5	7	20	46	89	51.7	18	43	41.9	22	24	91.7	19
Chicago Bulls	19	5/13/1993	CHI	vs	CLE	W 104-85	240	104	43	31	12	2	12	44	87	50.6	3	8	37.5	13	22	59.1	24
Indiana Pacers	18	4/15/2018	IND	@	CLE	W 98-80	240	98	44	19	12	4	11	36	79	45.6	11	28	39.3	15	25	60.0	21
Boston Celtics	18	5/3/2010	BOS	@	CLE	W 104-86	240	104	43	30	8	2	18	40	78	51.3	9	19	47.4	15	18	83.3	31
Detroit Pistons	18	5/21/2006	DET	vs	CLE	W 79-61	240	79	48	11	4	6	9	29	68	42.6	3	13	23.1	18	32	56.3	22
New York Knicks	18	4/12/1978	NYK	@	CLE	W 132-114	240	132	35	33	6	8	15	56	92	60.9				20	25	80.0	33
New Jersey Nets	17	5/7/1993	NJN	vs	CLE	W 96-79	240	96	46	31	12	14	20	44	84	52.4	5	9	55.6	3	3	100.0	15