LeBron James had his most assists in a playoff game in Game 1 of the 2020 First Round versus the Trail Blazers, with 16 assists.

lebron james most assists in a playoff game
8/18/2020James5/3/2018James6/4/2017James5/8/2015James6/3/2018James5/1/2018James4/15/2017James5/24/2015James6/21/2012James5/12/2008James5/2/2008James9/18/2020James5/19/2018James5/15/2018James4/15/2018James4/20/2017James6/19/2012James5/28/2009James4/21/2008James5/12/2007James5/8/2007James9/22/2020James6/6/2018James1614141413131313131313121212121212121212121111
NAMEDATETMOPPASTMINPTSREBSTLBLKTOVFGMFGAFG%3PM3PA3P%FTMFTAFT%PF+/-
LeBron JamesLeBron James8/18/2020LALLALvsPORPOR1641231710492045.01520.04757.11-3
LeBron JamesLeBron James5/3/2018CLECLE@TORTOR1441438101192867.91333.34850.01+20
LeBron JamesLeBron James6/4/2017CLECLE@GSWGSW14392911314121866.71333.34580.02-11
LeBron JamesLeBron James5/8/2015CLECLE@CHICHI144427811782532.01714.3101190.940
LeBron JamesLeBron James6/3/2018CLECLE@GSWGSW1344299205102050.02450.07977.82-18
LeBron JamesLeBron James5/1/2018CLECLE@TORTOR13472611121123040.01812.51616.72+5
LeBron JamesLeBron James4/15/2017CLECLEvsINDIND1343326303122060.02366.76966.73+5
LeBron JamesLeBron James5/24/2015CLECLEvsATLATL13473718306143737.81616.781080.04-3
LeBron JamesLeBron James6/21/2012MIAMIAvsOKCOKC1344261112691947.4030.08988.92+20
LeBron JamesLeBron James5/12/2008CLECLEvsBOSBOS134421632472035.02540.05862.53+15
LeBron JamesLeBron James5/2/2008CLECLE@WASWAS1344271321181747.11250.01010100.02+26
LeBron JamesLeBron James9/18/2020LALLALvsDENDEN123115600361154.5020.03475.02+15
LeBron JamesLeBron James5/19/2018CLECLEvsBOSBOS123827522381266.733100.081080.03+31
LeBron JamesLeBron James5/15/2018CLECLE@BOSBOS12394210016162955.251145.551050.03-9
LeBron JamesLeBron James4/15/2018CLECLEvsINDIND1244241011371741.2040.0101471.42-13
LeBron JamesLeBron James4/20/2017CLECLE@INDIND12454113123142751.961250.071450.04+13
LeBron JamesLeBron James6/19/2012MIAMIAvsOKCOKC1244269203102050.01425.05862.52+8
LeBron JamesLeBron James5/28/2009CLECLEvsORLORL12463714114112445.8020.0151978.93+11
LeBron JamesLeBron James4/21/2008CLECLEvsWASWAS123930912191947.42633.3101758.82+34
LeBron JamesLeBron James5/12/2007CLECLE@NJNNJN124418600251631.31520.077100.02-12
LeBron JamesLeBron James5/8/2007CLECLEvsNJNNJN1246361302122450.03742.991369.22+8
LeBron JamesLeBron James9/22/2020LALLAL@DENDEN11373010226142360.91425.01250.01+2
LeBron JamesLeBron James6/6/2018CLECLEvsGSWGSW11473310224132846.41616.76785.72-8
LeBron JamesLeBron James5/7/2018CLECLEvsTORTOR1138298212121963.2030.05862.52+28
LeBron JamesLeBron James6/9/2017CLECLEvsGSWGSW11413110102112250.03837.561060.02+32
Results may be incomplete. StatMuse has complete game-level data for assists going back to the 1965 playoffs.