LeBron James is 23-20 versus the Spurs in his career.

NAME	DATE	REC	TM		OPP	W%	MIN	PTS	REB	AST	STL	BLK	TOV	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	PF	+/-
LeBron James	2/20/2004	1-0	CLE	vs	SAS	1.000	39	32	11	2	2	1	2	14	23	60.9	0	0		4	4	100.0	0	+3
LeBron James	3/29/2004	0-1	CLE	@	SAS	.000	32	18	2	4	0	1	2	9	20	45.0	0	1	0.0	0	0		0	-14
LeBron James	12/11/2004	0-1	CLE	@	SAS	.000	42	23	6	10	4	0	3	10	19	52.6	1	3	33.3	2	2	100.0	2	-18
LeBron James	2/28/2005	0-1	CLE	vs	SAS	.000	45	20	8	7	0	0	2	6	22	27.3	1	4	25.0	7	10	70.0	3	+2
LeBron James	11/4/2005	0-1	CLE	@	SAS	.000	37	20	6	4	0	1	3	7	16	43.8	0	3	0.0	6	7	85.7	3	-19
LeBron James	2/13/2006	1-0	CLE	vs	SAS	1.000	41	44	3	5	4	0	2	19	33	57.6	1	3	33.3	5	8	62.5	0	+12
LeBron James	11/3/2006	1-0	CLE	@	SAS	1.000	42	35	10	4	1	1	2	14	26	53.8	1	2	50.0	6	11	54.5	3	+6
LeBron James	1/2/2007	1-0	CLE	vs	SAS	1.000	40	19	5	5	2	0	3	7	17	41.2	0	1	0.0	5	11	45.5	1	+5
LeBron James	1/17/2008	1-0	CLE	@	SAS	1.000	39	27	9	7	0	2	3	9	24	37.5	1	5	20.0	8	12	66.7	1	-11
LeBron James	2/13/2008	0-1	CLE	vs	SAS	.000	43	39	6	9	0	1	3	17	31	54.8	1	5	20.0	4	7	57.1	4	-1
LeBron James	2/27/2009	1-0	CLE	@	SAS	1.000	32	30	14	4	2	0	1	12	23	52.2	3	6	50.0	3	3	100.0	2	+29
LeBron James	4/5/2009	1-0	CLE	vs	SAS	1.000	37	38	7	6	1	0	2	14	21	66.7	2	5	40.0	8	8	100.0	1	+7
LeBron James	3/26/2010	0-1	CLE	@	SAS	.000	39	27	5	10	2	0	5	11	21	52.4	1	6	16.7	4	7	57.1	2	-5
LeBron James	3/4/2011	0-1	MIA	@	SAS	.000	36	26	8	7	1	0	4	11	19	57.9	1	3	33.3	3	7	42.9	2	-16
LeBron James	3/14/2011	1-0	MIA	vs	SAS	1.000	42	21	6	8	0	2	2	8	19	42.1	0	1	0.0	5	5	100.0	3	+22
LeBron James	1/17/2012	1-0	MIA	vs	SAS	1.000	35	33	5	10	0	0	4	12	21	57.1	4	6	66.7	5	9	55.6	0	+19
LeBron James	11/29/2012	1-0	MIA	vs	SAS	1.000	39	23	9	7	4	0	4	9	16	56.3	2	5	40.0	3	6	50.0	2	-1
LeBron James	1/26/2014	1-0	MIA	vs	SAS	1.000	28	18	7	6	1	0	4	8	15	53.3	1	3	33.3	1	1	100.0	4	+22
LeBron James	3/6/2014	0-1	MIA	@	SAS	.000	38	19	8	7	2	0	5	6	18	33.3	0	3	0.0	7	9	77.8	5	-10
LeBron James	11/19/2014	0-1	CLE	vs	SAS	.000	34	15	6	9	1	1	5	6	17	35.3	2	3	66.7	1	1	100.0	3	-3
LeBron James	3/12/2015	1-0	CLE	@	SAS	1.000	44	31	5	7	2	1	3	10	20	50.0	3	6	50.0	8	10	80.0	2	+3
LeBron James	1/14/2016	0-1	CLE	@	SAS	.000	37	22	7	5	0	0	4	9	17	52.9	1	3	33.3	3	4	75.0	4	+9
LeBron James	1/30/2016	1-0	CLE	vs	SAS	1.000	34	29	5	7	2	2	2	10	17	58.8	0	2	0.0	9	11	81.8	2	+14
LeBron James	1/21/2017	0-1	CLE	vs	SAS	.000	45	29	6	7	2	0	7	11	16	68.8	2	5	40.0	5	7	71.4	5	-16
LeBron James	3/27/2017	0-1	CLE	@	SAS	.000	30	17	8	8	0	0	2	7	17	41.2	0	3	0.0	3	6	50.0	3	-13