The 2005 roster for the Bills included Kelly Holcomb at quarterback, Willis McGahee at running back, Lee Evans at wide receiver, Mark Campbell at tight end and Mike Gandy at offensive lineman.
| NO. | NAME | POS | HEIGHT | WEIGHT | DOB | AGE | COLLEGE | ||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 95 |  | S. Adams | DL | 6'3" | 350 | 6/13/1973 | 32 | Texas A&M |
| 2 | 89 | | S. Aiken | WR | 6'2" | 220 | 12/14/1980 | 25 | North Carolina |
| 3 | 66 | | B. Anderson | OL | 6'5" | 345 | 2/17/1977 | 28 | Tennessee State |
| 4 | 77 | | T. Anderson | DL | 6'4" | 315 | 11/22/1980 | 25 | Ohio State |
| 5 | 26 | | R. Baker | DB | 5'10" | 200 | 2/22/1982 | 23 | Tennessee |
| 6 | 97 | | J. Bannan | DL | 6'3" | 312 | 4/18/1979 | 26 | Colorado |
| 7 | 35 | | J. Burns | RB | 5'9" | 215 | 9/15/1979 | 26 | Georgia Tech |
| 8 | 84 | | M. Campbell | TE | 6'6" | 260 | 12/6/1975 | 30 | Michigan |
| 9 | 48 | | B. Cieslak | TE | 6'3" | 260 | 7/1/1982 | 23 | Northern Illinois |
| 10 | 22 | | N. Clements | DB | 6'0" | 205 | 12/12/1979 | 26 | Ohio State |
| 11 | 55 | | A. Crowell | LB | 6'1" | 246 | 8/16/1981 | 24 | Virginia |
| 12 | 92 | | R. Denney | DL | 6'7" | 264 | 6/15/1977 | 28 | Brigham Young |
| 13 | 98 | | R. Edwards | DL | 6'3" | 325 | 7/12/1979 | 26 | Texas A&M |
| 14 | 87 | | T. Euhus | TE | 6'5" | 256 | 10/2/1980 | 25 | Oregon State |
| 15 | 83 | | L. Evans | WR | 6'0" | 210 | 3/11/1981 | 24 | Wisconsin |
| 16 | 50 | | L. Ezekiel | LB | 6'0" | 249 | 10/30/1982 | 23 | Northeastern |
| 17 | 59 |  | L. Fletcher | LB | 5'10" | 242 | 5/19/1975 | 30 | John Carroll |
| 18 | 69 | | M. Gandy | OL | 6'4" | 316 | 1/3/1979 | 26 | Notre Dame |
| 19 | 33 | | J. Greer | DB | 5'11" | 180 | 2/11/1982 | 23 | Tennessee |
| 20 | 53 | | M. Haggan | LB | 6'3" | 274 | 3/3/1980 | 25 | Mississippi State |
| 21 | 10 | | K. Holcomb | QB | 6'2" | 216 | 7/9/1973 | 32 | Middle Tennessee |
| 22 | 99 | | J. Jefferson | DL | 6'1" | 297 | 12/20/1981 | 24 | Wisconsin |
| 23 | 76 | | G. Jerman | OL | 6'5" | 310 | 1/24/1979 | 26 | Baylor |
| 24 | 90 | | C. Kelsay | DL | 6'4" | 263 | 10/31/1979 | 26 | Nebraska |
| 25 | 29 | | E. King | DB | 5'10" | 190 | 5/10/1982 | 23 | Wake Forest |
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More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |