The 2021 roster for the Bills included Josh Allen at quarterback, Devin Singletary at running back, Stefon Diggs at wide receiver, Dawson Knox at tight end and Mitch Morse at offensive lineman.
| NO. | NAME | POS | HEIGHT | WEIGHT | DOB | AGE | COLLEGE | ||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 97 |  | M. Addison | DL | 6'3" | 260 | 9/6/1987 | 34 | Troy |
| 2 | 17 |  | J. Allen | QB | 6'5" | 237 | 5/21/1996 | 25 | Wyoming |
| 3 | 0 | | E. Ankou | DL | 6'3" | 325 | 6/8/1994 | 27 | UCLA |
| 4 | 5 | | M. Barkley | QB | 6'2" | 234 | 9/8/1990 | 31 | Southern California |
| 5 | 96 | | B. Basham | DL | 6'5" | 285 | 12/16/1997 | 24 | Wake Forest |
| 6 | 2 | | T. Bass | K | 5'10" | 185 | 2/14/1997 | 24 | Georgia Southern |
| 7 | 71 | | R. Bates | OL | 6'4" | 302 | 2/14/1997 | 24 | Penn State |
| 8 | 11 |  | C. Beasley | WR | 5'8" | 174 | 4/26/1989 | 32 | Southern Methodist |
| 9 | 65 | | I. Boettger | OL | 6'6" | 313 | 10/5/1994 | 27 | Iowa |
| 10 | 22 |  | M. Breida | RB | 5'11" | 195 | 2/28/1995 | 26 | Georgia Southern |
| 11 | 79 | | S. Brown | OL | 6'9" | 321 | 2/28/1998 | 23 | Northern Iowa |
| 12 | 90 | | B. Bryant | DL | 6'2" | 289 | 9/16/1993 | 28 | Florida Atlantic |
| 13 | 94 | | V. Butler | DL | 6'4" | 330 | 6/14/1994 | 27 | Louisiana Tech |
| 14 | 66 | | J. Capra | OL | 6'4" | 300 | 11/2/1998 | 23 | San Diego State |
| 15 | 51 | | B. Cox | DL | 6'3" | 270 | 6/25/1994 | 27 | Florida |
| 16 | 13 |  | G. Davis | WR | 6'3" | 213 | 4/1/1999 | 22 | Central Florida |
| 17 | 73 | | D. Dawkins | OL | 6'5" | 320 | 4/26/1994 | 27 | Temple |
| 18 | 14 |  | S. Diggs | WR | 6'0" | 191 | 11/29/1993 | 28 | Maryland |
| 19 | 53 | | T. Dodson | LB | 6'2" | 240 | 6/25/1998 | 23 | Texas A&M |
| 20 | 77 | | J. Douglas | OL | 6'4" | 309 | 2/28/1992 | 29 | Arizona State |
| 21 | 72 | | T. Doyle | OL | 6'8" | 326 | 5/6/1998 | 23 | Miami (OH) |
| 22 | 49 | | T. Edmunds | LB | 6'5" | 250 | 5/2/1998 | 23 | Virginia Tech |
| 23 | 57 | | A.J. Epenesa | DL | 6'5" | 280 | 9/15/1998 | 23 | Iowa |
| 24 | 76 | | J. Feliciano | OL | 6'4" | 325 | 2/10/1992 | 29 | Miami (FL) |
| 25 | 69 | | R. Ferguson | LS | 6'2" | 235 | 3/24/1994 | 27 | Louisiana State |
More Bills Stats
Team Rankings
PPG
30.6
3rd
OPP PPG
22.6
17th
RUSH YDS/G
154.4
2nd
PASS YDS/G
249.8
11th
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| NFC East | W | L | T | PCT |
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 Eagles | 4 | 2 | 0 | .667 |
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| NFC North | W | L | T | PCT |
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 49ers | 4 | 1 | 0 | .800 |
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