| TEAM | OPPONENT | WEEK/ROUND | DATE | TIME (ET) | SPREAD | OVER/UNDER | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | San Francisco 49ers | -132 | vs |  Atlanta Falcons | +111 | WK 7 | Sun, Oct 19, 2025 | 8:20 PM | -2.0 | 47.0 |
| 2 | | San Francisco 49ers | +108 | @ |  Houston Texans | -127 | WK 8 | Sun, Oct 26, 2025 | 1:00 PM | +1.5 | 43.5 |
| 3 | | San Francisco 49ers | -189 | @ |  New York Giants | +150 | WK 9 | Sun, Nov 2, 2025 | 1:00 PM | -3.5 | 45.0 |
| 4 | | San Francisco 49ers | -135 | vs |  Los Angeles Rams | +105 | WK 10 | Sun, Nov 9, 2025 | 4:25 PM | -1.5 | 46.5 |
| 5 | | San Francisco 49ers | -130 | @ |  Arizona Cardinals | +100 | WK 11 | Sun, Nov 16, 2025 | 4:05 PM | -1.5 | 47.5 |
| 6 | | San Francisco 49ers | -294 | vs |  Carolina Panthers | +220 | WK 12 | Mon, Nov 24, 2025 | 8:15 PM | -6.5 | 46.5 |
| 7 | | San Francisco 49ers | -233 | @ |  Cleveland Browns | +180 | WK 13 | Sun, Nov 30, 2025 | 1:00 PM | -5.5 | 43.5 |
Betting lines shown represent consensus, closing odds.
More 49ers Stats
Team Rankings
PPG
20.8
24th
OPP PPG
21.3
15th
RUSH YDS/G
82.2
30th
PASS YDS/G
306.3
1st
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
Patriots 
Bills 
Steelers 
Bengals 
Colts 
Jaguars 
Chargers 
Broncos | NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 2 | 0 | .667 |
 Commanders | 3 | 3 | 0 | .500 |
| NFC North | W | L | T | PCT |
 Packers | 3 | 1 | 1 | .700 |
 Lions | 4 | 2 | 0 | .667 |
| NFC South | W | L | T | PCT |
 Buccaneers | 5 | 1 | 0 | .833 |
| Falcons | 3 | 2 | 0 | .600 |
| NFC West | W | L | T | PCT |
 49ers | 4 | 2 | 0 | .667 |
 Seahawks | 4 | 2 | 0 | .667 |
DAL 
KC 
NYJ 
LV 
TEN 
NO 
CHI 
MIA 
