The San Francisco 49ers are 55-36-4 against the spread against the Rams in their last 100 games.

	TEAM	DATE	ATS	TM		OPP	RESULT	SPREAD	ATS DIFF	O/U	O/U DIFF	TD	1DWN	OFF	OPP OFF
1	49ers	9/16/1979	1-0	SF	@	LA	L 24-27	+13	+10 (Y)	39	+12 (O)	3	17	239	387
2	49ers	11/25/1979	0-0-1	SF	vs	LA	L 20-26	+6	0 (P)	39	+7 (O)	2	22	374	322
3	49ers	10/5/1980	0-1	SF	@	LA	L 26-48	+9	-13 (N)	48	+26 (O)	4	25	419	462
4	49ers	10/19/1980	0-1	SF	vs	LA	L 17-31	+9	-5 (N)	50	-2 (U)	2	22	353	419
5	49ers	10/25/1981	1-0	SF	vs	LA	W 20-17	-1	+2 (Y)	46	-9 (U)	2	14	325	401
6	49ers	11/22/1981	1-0	SF	@	LA	W 33-31	+3	+5 (Y)	42	+22 (O)	3	19	330	411
7	49ers	12/2/1982	1-0	SF	@	RAM	W 30-24	-2.5	+3.5 (Y)	42	+12 (O)	3	21	375	341
8	49ers	1/2/1983	0-1	SF	vs	RAM	L 20-21	-10	-11 (N)	51	-10 (U)	3	18	324	374
9	49ers	10/9/1983	0-1	SF	vs	RAM	L 7-10	-4.5	-7.5 (N)	48	-31 (U)	1	20	381	307
10	49ers	10/23/1983		SF	@	RAM	W 45-35			45	+35 (O)	6	22	460	441
11	49ers	10/28/1984	1-0	SF	@	RAM	W 33-0	-3	+30 (Y)	45	-12 (U)	4	23	472	206
12	49ers	12/14/1984	0-1	SF	vs	RAM	W 19-16	-6	-3 (N)	44	-9 (U)	2	15	289	355
13	49ers	10/27/1985	1-0	SF	@	RAM	W 28-14	-1	+13 (Y)	38.5	+3.5 (O)	4	23	429	401
14	49ers	12/9/1985	0-1	SF	vs	RAM	L 20-27	-10	-17 (N)	41	+6 (O)	3	22	410	264
15	49ers	9/14/1986	0-1	SF	@	RAM	L 13-16	-3	-6 (N)	37.5	-8.5 (U)	1	13	325	192
16	49ers	12/19/1986	1-0	SF	vs	RAM	W 24-14	-4	+6 (Y)	39.5	-1.5 (U)	3	27	408	229
17	49ers	11/1/1987	1-0	SF	@	RAM	W 31-10	-5	+16 (Y)	42	-1 (U)	4	23	435	280
18	49ers	12/27/1987	1-0	SF	vs	RAM	W 48-0	-9.5	+38.5 (Y)	41	+7 (O)	7	23	427	145
19	49ers	10/16/1988		SF	@	RAM	W 24-21			43	+2 (O)	3	24	429	236
20	49ers	12/18/1988	0-1	SF	vs	RAM	L 16-38	-5	-27 (N)	42	+12 (O)	1	20	316	322
21	49ers	10/1/1989	0-1	SF	vs	RAM	L 12-13	-4	-5 (N)	47	-22 (U)	0	22	367	287
22	49ers	12/11/1989	1-0	SF	@	RAM	W 30-27	-2.5	+0.5 (Y)	44.5	+12.5 (O)	4	25	502	337
23	49ers	1/14/1990	1-0	SF	vs	RAM	W 30-3	-7	+20 (Y)	45	-12 (U)	3	29	443	156
24	49ers	11/25/1990	0-1	SF	vs	RAM	L 17-28	-11	-22 (N)	46	-1 (U)	2	16	291	350
25	49ers	12/17/1990	1-0	SF	@	RAM	W 26-10	-6.5	+9.5 (Y)	46	-10 (U)	3	21	388	266
	Average		0.6									2.9	19.8	350.8	307.1
	Total		55-36-4									286	1,922	34,031	29,793

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StatMuse has team, game-level data for spread records going back to the 1979 season.

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More 49ers Stats

Team Leaders

PASS

492

Purdy

RUSH

91

McCaffrey

REC

103

Evans

Team Rankings

PPG

31.0

4th

OPP PPG

10.0

3rd

RUSH YDS/G

134.5

8th

PASS YDS/G

246.0

10th

2026 Division Standings

TEAM	W	L	PCT
49ers	2	0	1.000
Seahawks	2	0	1.000
Cardinals	1	1	.500
Rams	1	1	.500

Schedule

DATE	MATCHUP			TIME (ET)
Sun 9/27	ARI	@	SF	4:05 PM
Sun 10/4	DEN	@	SF	4:25 PM
Sun 10/11	SF	@	SEA	4:25 PM
Mon 10/19	WAS	@	SF	8:15 PM
Sun 10/25	SF	@	ATL	1:00 PM

Last Game

Dolphins

0 - 2

Final

49ers

2 - 0

Sun 20 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

662

Shough

648

Young

627

Stroud

Rush Yards Leaders

290

Walker

212

Henry

208

Gibbs

Rec Yards Leaders

277

Smith-Njigba

268

Olave

225

Kincaid

Pass TD Leaders

6

Young

6

Prescott

6

Goff

Rush TD Leaders

4

Taylor

4

Allen

4

Henry

Rec TD Leaders

4

Smith-Njigba

4

St. Brown

3

Watson

QB Rating Leaders

127.3

Lock

125.9

Dart

125.8

Allen

Sack Leaders

4.0

Rousseau

3.5

Watt

3.0

Hutchinson

NFL 2026 Rankings

PPG Rankings

38.5

35.5

32.0

31.0

Opp PPG Rankings

8.0

8.5

10.0

12.5

13.5

15.0

Total Yards Rankings

457.5

427.5

424.5

409.0

385.5

Rush Yards Rankings

212.5

186.0

157.0

155.0

144.5

142.5

Pass Yards Rankings

331.0

324.0

313.5

291.0

283.0

279.5

Sack Leaders

8.0

7.0

NFL Fantasy 2026

Fantasy RB Rankings

49

Henry

48.9

Walker

47.3

Taylor

Fantasy WR Rankings

51.7

Smith-Njigba

44.9

St. Brown

37.7

Lamb

Fantasy TE Rankings

28.5

Kincaid

25.6

McBride

23.2

Kelce

Fantasy K Rankings

31

McPherson

27

McLaughlin

24

Butker

NFL 2026 Betting

Best Record ATS

2-0

Worst Record ATS

0-2

NFL 2026 Standings

NFC East	W	L	T	PCT
Eagles	2	0	0	1.000
Giants	1	1	0	.500
Cowboys	1	1	0	.500
Commanders	0	2	0	.000
NFC North	W	L	T	PCT
Vikings	2	0	0	1.000
Lions	1	1	0	.500
Bears	1	1	0	.500
Packers	1	1	0	.500
NFC South	W	L	T	PCT
Panthers	1	1	0	.500
Saints	1	1	0	.500
Buccaneers	0	2	0	.000
Falcons	0	2	0	.000
NFC West	W	L	T	PCT
Seahawks	2	0	0	1.000
49ers	2	0	0	1.000
Rams	1	1	0	.500
Cardinals	1	1	0	.500

AFC East	W	L	T	PCT
Bills	2	0	0	1.000
Patriots	1	1	0	.500
Jets	1	1	0	.500
Dolphins	0	2	0	.000
AFC North	W	L	T	PCT
Bengals	2	0	0	1.000
Ravens	1	1	0	.500
Steelers	1	1	0	.500
Browns	1	1	0	.500
AFC South	W	L	T	PCT
Jaguars	1	1	0	.500
Titans	0	2	0	.000
Texans	0	2	0	.000
Colts	0	2	0	.000
AFC West	W	L	T	PCT
Chiefs	2	0	0	1.000
Raiders	2	0	0	1.000
Broncos	1	1	0	.500
Chargers	0	2	0	.000