The Buffalo Bills were 12-5 this season. They finished 2nd in the AFC East and 6th in the AFC. They emerged victorious over the Jacksonville Jaguars, 27 to 24, in the 2025 AFC Wild Card game.
| GP | PTS | YDS | PLY | AVG | RUSH YDS | RUSH ATT | RUSH AVG | PASS YDS | PASS ATT | PASS AVG | SCK | SCKY | 1DWN | RUSH 1DWN | PASS 1DWN | PEN 1DWN | PEN | PEN YDS | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Team | 17 | 481 | 6,397 | 1,082 | 5.9 | 2,714 | 547 | 5.0 | 3,981 | 495 | 8.0 | 40 | 298 | 374 | 146 | 196 | 32 | 101 | 848 |
Team Rank | 4th | 4th | 9th | 5th | 1st | 1st | 2nd | 13th | 25th | 3rd | 19th | 10th | 4th | 1st | 9th | 13th | 9th | 16th | |
Opponent | 17 | 365 | 4,983 | 950 | 5.2 | 2,315 | 450 | 5.1 | 2,894 | 464 | 6.2 | 36 | 226 | 300 | 130 | 144 | 26 | 83 | 731 |
Opponent Rank | 12th | 7th | 1st | 15th | 28th | 14th | 30th | 1st | 2nd | 4th | 20th | 11th | 7th | 24th | 2nd | 6th | 32nd | 30th | |
Net | +116 | +1,414 | +132 | +0.7 | +399 | +97 | -0.2 | +1,087 | +31 | +1.8 | +4 | +72 | +74 | +16 | +52 | +6 | +18 | +117 | |
Net Rank | 5th | 2nd | 1st | 5th | 6th | 2nd | 26th | 1st | 12th | 3rd | 18th | 8th | 1st | 11th | 1st | 9th | 27th | 28th |
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
14 | 3 | 0 | .824 | |
12 | 5 | 0 | .706 | |
7 | 10 | 0 | .412 | |
3 | 14 | 0 | .176 | |
| AFC North | W | L | T | PCT |
10 | 7 | 0 | .588 | |
8 | 9 | 0 | .471 | |
6 | 11 | 0 | .353 | |
5 | 12 | 0 | .294 | |
| AFC South | W | L | T | PCT |
13 | 4 | 0 | .765 | |
12 | 5 | 0 | .706 | |
8 | 9 | 0 | .471 | |
3 | 14 | 0 | .176 | |
| AFC West | W | L | T | PCT |
14 | 3 | 0 | .824 | |
11 | 6 | 0 | .647 | |
6 | 11 | 0 | .353 | |
3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
11 | 6 | 0 | .647 | |
7 | 9 | 1 | .441 | |
5 | 12 | 0 | .294 | |
4 | 13 | 0 | .235 | |
| NFC North | W | L | T | PCT |
11 | 6 | 0 | .647 | |
9 | 7 | 1 | .559 | |
9 | 8 | 0 | .529 | |
9 | 8 | 0 | .529 | |
| NFC South | W | L | T | PCT |
8 | 9 | 0 | .471 | |
8 | 9 | 0 | .471 | |
8 | 9 | 0 | .471 | |
6 | 11 | 0 | .353 | |
| NFC West | W | L | T | PCT |
14 | 3 | 0 | .824 | |
12 | 5 | 0 | .706 | |
12 | 5 | 0 | .706 | |
3 | 14 | 0 | .176 |