The Buffalo Bills have a 73-69-5 record against the spread in the regular season against the AFC since 2014.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 9/14/2014 | 1-0 | -120 | vs | +100 | W 29-10 | -1 | +18 (Y) | 43 | -4 (U) | 2 | 13 | 315 | 290 | 33.3 | |||
| 2 | | Bills | 9/21/2014 | 0-1 | -140 | vs | +120 | L 10-22 | -2.5 | -14.5 (N) | 45.5 | -13.5 (U) | 1 | 18 | 292 | 333 | 42.9 | 0.0 | ||
| 3 | | Bills | 9/28/2014 | 0-1 | +130 | @ | -150 | L 17-23 | +3 | -3 (N) | 44 | -4 (U) | 2 | 17 | 316 | 301 | 31.3 | |||
| 4 | | Bills | 10/12/2014 | 0-1 | -105 | vs | -115 | L 22-37 | +1 | -14 (N) | 44.5 | +14.5 (O) | 3 | 19 | 336 | 396 | 53.3 | 50.0 | ||
| 5 | | Bills | 10/26/2014 | 1-0 | +130 | @ | -150 | W 43-23 | +3 | +23 (Y) | 40.5 | +25.5 (O) | 5 | 12 | 280 | 312 | 25.0 | |||
| 6 | | Bills | 11/9/2014 | 0-1 | -125 | vs | +105 | L 13-17 | -2 | -6 (N) | 42 | -12 (U) | 1 | 21 | 364 | 278 | 43.8 | 0.0 | ||
| 7 | | Bills | 11/13/2014 | 0-1 | +175 | @ | -210 | L 9-22 | +3.5 | -9.5 (N) | 41.5 | -10.5 (U) | 0 | 13 | 237 | 330 | 40.0 | 0.0 | ||
| 8 | | Bills | 11/24/2014 | 1-0 | -145 | vs | +125 | W 38-3 | -2 | +33 (Y) | 42 | -1 (U) | 5 | 21 | 336 | 218 | 53.8 | 0.0 | ||
| 9 | | Bills | 11/30/2014 | 1-0 | -170 | vs | +150 | W 26-10 | -3 | +13 (Y) | 42 | -6 (U) | 2 | 15 | 287 | 315 | 13.3 | 100.0 | ||
| 10 | | Bills | 12/7/2014 | 1-0 | +350 | @ | -425 | L 17-24 | +9 | +2 (Y) | 47 | -6 (U) | 2 | 24 | 415 | 306 | 56.3 | 66.7 | ||
| 11 | | Bills | 12/21/2014 | 0-1 | -280 | @ | +240 | L 24-26 | -7 | -9 (N) | 42 | +8 (O) | 3 | 15 | 321 | 347 | 26.7 | |||
| 12 | | Bills | 12/28/2014 | 1-0 | +175 | @ | -210 | W 17-9 | +4 | +12 (Y) | 44 | -18 (U) | 2 | 16 | 268 | 260 | 45.5 | |||
| 13 | | Bills | 9/13/2015 | 1-0 | -105 | vs | -115 | W 27-14 | +1 | +14 (Y) | 44 | -3 (U) | 3 | 15 | 342 | 304 | 38.5 | |||
| 14 | | Bills | 9/20/2015 | 0-1 | -119 | vs | -101 | L 32-40 | -2 | -10 (N) | 45 | +27 (O) | 5 | 23 | 349 | 507 | 30.8 | 100.0 | ||
| 15 | | Bills | 9/27/2015 | 1-0 | +105 | @ | -125 | W 41-14 | +2 | +29 (Y) | 44 | +11 (O) | 5 | 21 | 428 | 391 | 53.8 | |||
| 16 | | Bills | 10/11/2015 | 0-0-1 | -115 | @ | -105 | W 14-13 | -1 | 0 (P) | 43 | -16 (U) | 2 | 13 | 209 | 276 | 33.3 | |||
| 17 | | Bills | 10/18/2015 | 0-1 | +144 | vs | -164 | L 21-34 | +3 | -10 (N) | 42 | +13 (O) | 3 | 22 | 368 | 355 | 38.5 | 50.0 | ||
| 18 | | Bills | 10/25/2015 | 0-1 | -200 | @ | +160 | L 31-34 | -4 | -7 (N) | 42 | +23 (O) | 3 | 26 | 375 | 295 | 25.0 | 0.0 | ||
| 19 | | Bills | 11/8/2015 | 1-0 | -200 | vs | +167 | W 33-17 | -4 | +12 (Y) | 44 | +6 (O) | 4 | 18 | 420 | 397 | 61.5 | |||
| 20 | | Bills | 11/12/2015 | 1-0 | +115 | @ | -135 | W 22-17 | +2 | +7 (Y) | 42 | -3 (U) | 2 | 13 | 280 | 318 | 31.3 | 0.0 | ||
| 21 | | Bills | 11/23/2015 | 0-0-1 | +290 | @ | -350 | L 13-20 | +7 | 0 (P) | 48 | -15 (U) | 1 | 16 | 319 | 356 | 20.0 | 100.0 | ||
| 22 | | Bills | 11/29/2015 | 0-1 | +185 | @ | -215 | L 22-30 | +4 | -4 (N) | 41 | +11 (O) | 3 | 25 | 415 | 413 | 41.7 | 0.0 | ||
| 23 | | Bills | 12/6/2015 | 1-0 | -155 | vs | +135 | W 30-21 | -3 | +6 (Y) | 42 | +9 (O) | 4 | 15 | 390 | 401 | 50.0 | |||
| 24 | | Bills | 1/3/2016 | 1-0 | +130 | vs | -150 | W 22-17 | +3 | +8 (Y) | 41 | -2 (U) | 2 | 18 | 295 | 300 | 45.0 | 100.0 | ||
| 25 | | Bills | 9/11/2016 | 0-1 | +130 | @ | -150 | L 7-13 | +3 | -3 (N) | 45 | -25 (U) | 1 | 11 | 160 | 308 | 23.1 | 100.0 | ||
| Average | 0.3 | 2.8 | 20.4 | 350.5 | 317.8 | 41.8 | 0.0 | |||||||||||||
| Total | 73-69-5 | 416 | 2,999 | 51,529 | 46,714 | 41.8 | 51.5 | |||||||||||||
BUF
MIA
SD
HOU
NE
NYJ
KC
CLE
DEN
OAK
IND
TEN
CIN
JAX
BALStatMuse has team, game-level data for spread records going back to the 1979 season.
More NFL News
LA Rams sign Brandon McManus, their third kicker in 2 weeks
Key moments in Eagles quarterback Jalen Hurts being diagnosed with blood clots in his lungs
The 49ers are in no mood to celebrate following 6th straight win to open the season
Commanders' Terry McLaurin to miss remainder of season with torn patellar tendon in left knee
Philadelphia Eagles are not being disciplined for how they handled quarterback Jalen Hurts’ blood clots, AP source says
Dolphins release kicker Riley Patterson, add Zane Gonzalez to practice squad
More Bills Stats
Team Leaders 
PASS
1,504
Allen
RUSH
627
Cook
REC
315
Kincaid
Team Rankings
PPG
32.8
1st
OPP PPG
28.5
28th
RUSH YDS/G
148.8
5th
PASS YDS/G
250.7
11th
Jets
MIN
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 2 | 1 | .583 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 | |
1 | 4 | 1 | .250 | |
| NFC North | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
4 | 2 | 0 | .667 | |
4 | 2 | 0 | .667 | |
3 | 2 | 0 | .600 | |
| NFC South | W | L | T | PCT |
3 | 2 | 0 | .600 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 | |
1 | 5 | 0 | .167 | |
| NFC West | W | L | T | PCT |
6 | 0 | 0 | 1.000 | |
3 | 3 | 0 | .500 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 |
Giants
Eagles
Cowboys
Commanders
Packers
Bears
Lions
Panthers
Falcons
Saints
Buccaneers
49ers
Seahawks
Cardinals
Rams| AFC East | W | L | T | PCT |
|---|---|---|---|---|
5 | 1 | 0 | .833 | |
4 | 2 | 0 | .667 | |
2 | 4 | 0 | .333 | |
0 | 5 | 0 | .000 | |
| AFC North | W | L | T | PCT |
4 | 2 | 0 | .667 | |
4 | 2 | 0 | .667 | |
4 | 2 | 0 | .667 | |
3 | 2 | 0 | .600 | |
| AFC South | W | L | T | PCT |
4 | 2 | 0 | .667 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 | |
1 | 5 | 0 | .167 | |
| AFC West | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
4 | 2 | 0 | .667 | |
3 | 3 | 0 | .500 | |
0 | 6 | 0 | .000 |
Steelers