The Buffalo Bills have a 3-5 record as favorites in the regular season and playoffs against the AFC South on the road since 2014.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 10/11/2015 | 1-0 | @ | W 14-13 | 1.000 | 2 | 13 | 209 | 276 | 33.3 | |||
| 2 | | Bills | 10/25/2015 | 0-1 | @ | L 31-34 | .000 | 3 | 26 | 375 | 295 | 25.0 | 0.0 | ||
| 3 | | Bills | 10/13/2020 | 0-1 | @ | L 16-42 | .000 | 2 | 23 | 370 | 334 | 76.5 | |||
| 4 | | Bills | 10/18/2021 | 0-1 | @ | L 31-34 | .000 | 3 | 28 | 417 | 362 | 53.8 | 0.0 | ||
| 5 | | Bills | 11/7/2021 | 0-1 | @ | L 6-9 | .000 | 0 | 17 | 301 | 218 | 40.0 | 0.0 | ||
| 6 | | Bills | 11/10/2024 | 1-0 | @ | W 30-20 | 1.000 | 3 | 21 | 415 | 361 | 50.0 | 66.7 | ||
| 7 | | Bills | 11/20/2025 | 0-1 | @ | L 19-23 | .000 | 2 | 14 | 326 | 261 | 31.3 | 60.0 | ||
| 8 | | Bills | 9/13/2026 | 1-0 | @ | W 36-31 | 1.000 | 4 | 20 | 409 | 381 | 33.3 | 0.0 | ||
| Average | .375 | 2.4 | 20.3 | 352.8 | 311.0 | 44.4 | 0.1 | ||||||||
| Total | 3-5 | .375 | 19 | 162 | 2,822 | 2,488 | 44.4 | 41.7 |
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More Bills Stats
Team Leaders 
PASS
1,504
Allen
RUSH
627
Cook
REC
315
Kincaid
Team Rankings
PPG
32.8
1st
OPP PPG
28.5
30th
RUSH YDS/G
148.8
2nd
PASS YDS/G
250.7
11th
Patriots
Jets
Dolphins
BAL
MIN
KC
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 2 | 1 | .643 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
1 | 4 | 1 | .250 | |
| NFC North | W | L | T | PCT |
6 | 0 | 0 | 1.000 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| NFC South | W | L | T | PCT |
3 | 3 | 0 | .500 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
| NFC West | W | L | T | PCT |
6 | 1 | 0 | .857 | |
4 | 3 | 0 | .571 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 |
Giants
Cowboys
Eagles
Commanders
Bears
Lions
Packers
Panthers
Falcons
Buccaneers
Saints
49ers
Seahawks
Rams
Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
5 | 1 | 0 | .833 | |
4 | 3 | 0 | .571 | |
2 | 5 | 0 | .286 | |
1 | 5 | 0 | .167 | |
| AFC North | W | L | T | PCT |
5 | 2 | 0 | .714 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| AFC South | W | L | T | PCT |
4 | 2 | 0 | .667 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
1 | 6 | 0 | .143 | |
| AFC West | W | L | T | PCT |
5 | 1 | 0 | .833 | |
5 | 2 | 0 | .714 | |
3 | 4 | 0 | .429 | |
0 | 6 | 0 | .000 |
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Chargers