The Buffalo Bills have a record of 44-38-1 against the spread in the regular season and playoffs against the AFC at home since 2014.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 9/14/2014 | 1-0 | -120 | vs | +100 | W 29-10 | -1 | +18 (Y) | 43 | -4 (U) | 2 | 13 | 315 | 290 | 33.3 | |||
| 2 | | Bills | 9/21/2014 | 0-1 | -140 | vs | +120 | L 10-22 | -2.5 | -14.5 (N) | 45.5 | -13.5 (U) | 1 | 18 | 292 | 333 | 42.9 | 0.0 | ||
| 3 | | Bills | 10/12/2014 | 0-1 | -105 | vs | -115 | L 22-37 | +1 | -14 (N) | 44.5 | +14.5 (O) | 3 | 19 | 336 | 396 | 53.3 | 50.0 | ||
| 4 | | Bills | 11/9/2014 | 0-1 | -125 | vs | +105 | L 13-17 | -2 | -6 (N) | 42 | -12 (U) | 1 | 21 | 364 | 278 | 43.8 | 0.0 | ||
| 5 | | Bills | 11/24/2014 | 1-0 | -145 | vs | +125 | W 38-3 | -2 | +33 (Y) | 42 | -1 (U) | 5 | 21 | 336 | 218 | 53.8 | 0.0 | ||
| 6 | | Bills | 11/30/2014 | 1-0 | -170 | vs | +150 | W 26-10 | -3 | +13 (Y) | 42 | -6 (U) | 2 | 15 | 287 | 315 | 13.3 | 100.0 | ||
| 7 | | Bills | 9/13/2015 | 1-0 | -105 | vs | -115 | W 27-14 | +1 | +14 (Y) | 44 | -3 (U) | 3 | 15 | 342 | 304 | 38.5 | |||
| 8 | | Bills | 9/20/2015 | 0-1 | -119 | vs | -101 | L 32-40 | -2 | -10 (N) | 45 | +27 (O) | 5 | 23 | 349 | 507 | 30.8 | 100.0 | ||
| 9 | | Bills | 10/18/2015 | 0-1 | +144 | vs | -164 | L 21-34 | +3 | -10 (N) | 42 | +13 (O) | 3 | 22 | 368 | 355 | 38.5 | 50.0 | ||
| 10 | | Bills | 11/8/2015 | 1-0 | -200 | vs | +167 | W 33-17 | -4 | +12 (Y) | 44 | +6 (O) | 4 | 18 | 420 | 397 | 61.5 | |||
| 11 | | Bills | 12/6/2015 | 1-0 | -155 | vs | +135 | W 30-21 | -3 | +6 (Y) | 42 | +9 (O) | 4 | 15 | 390 | 401 | 50.0 | |||
| 12 | | Bills | 1/3/2016 | 1-0 | +130 | vs | -150 | W 22-17 | +3 | +8 (Y) | 41 | -2 (U) | 2 | 18 | 295 | 300 | 45.0 | 100.0 | ||
| 13 | | Bills | 9/15/2016 | 0-1 | -115 | vs | -105 | L 31-37 | -1 | -7 (N) | 40.5 | +27.5 (O) | 4 | 16 | 393 | 493 | 30.0 | 50.0 | ||
| 14 | | Bills | 10/30/2016 | 0-1 | +210 | vs | -238 | L 25-41 | +5.5 | -10.5 (N) | 48 | +18 (O) | 3 | 25 | 376 | 357 | 30.8 | 50.0 | ||
| 15 | | Bills | 11/27/2016 | 0-1 | -400 | vs | +330 | W 28-21 | -8.5 | -1.5 (N) | 44 | +5 (O) | 4 | 15 | 304 | 301 | 41.7 | 100.0 | ||
| 16 | | Bills | 12/11/2016 | 0-1 | +105 | vs | -125 | L 20-27 | +2 | -5 (N) | 46 | +1 (O) | 3 | 14 | 275 | 460 | 33.3 | |||
| 17 | | Bills | 12/18/2016 | 1-0 | -500 | vs | +350 | W 33-13 | -10.5 | +9.5 (Y) | 43 | +3 (O) | 4 | 29 | 451 | 269 | 44.4 | 0.0 | ||
| 18 | | Bills | 12/24/2016 | 0-1 | -220 | vs | +185 | L 31-34 | -4.5 | -7.5 (N) | 44 | +21 (O) | 4 | 30 | 589 | 494 | 44.4 | 50.0 | ||
| 19 | | Bills | 9/10/2017 | 1-0 | -360 | vs | +325 | W 21-12 | -7.5 | +1.5 (Y) | 42.5 | -9.5 (U) | 3 | 23 | 408 | 214 | 47.1 | |||
| 20 | | Bills | 9/24/2017 | 1-0 | +160 | vs | -170 | W 26-16 | +3.5 | +13.5 (Y) | 40 | +2 (O) | 2 | 16 | 272 | 366 | 37.5 | |||
| 21 | | Bills | 10/29/2017 | 1-0 | -122 | vs | +112 | W 34-14 | -2 | +18 (Y) | 47.5 | +0.5 (O) | 4 | 17 | 331 | 367 | 40.0 | 100.0 | ||
| 22 | | Bills | 12/3/2017 | 0-1 | +305 | vs | -335 | L 3-23 | +7.5 | -12.5 (N) | 49 | -23 (U) | 0 | 16 | 268 | 435 | 38.5 | 0.0 | ||
| 23 | | Bills | 12/10/2017 | 1-0 | -180 | vs | +160 | W 13-7 | -3 | +3 (Y) | 36.5 | -16.5 (U) | 2 | 14 | 319 | 227 | 55.6 | 0.0 | ||
| 24 | | Bills | 12/17/2017 | 1-0 | -185 | vs | +170 | W 24-16 | -3.5 | +4.5 (Y) | 39.5 | +0.5 (O) | 3 | 21 | 328 | 349 | 46.7 | 0.0 | ||
| 25 | | Bills | 9/16/2018 | 0-1 | +270 | vs | -307 | L 20-31 | +7.5 | -3.5 (N) | 41.5 | +9.5 (O) | 2 | 17 | 293 | 349 | 35.7 | |||
| Average | 0.6 | 3.2 | 21.1 | 359.9 | 319.3 | 43.0 | 0.0 | |||||||||||||
| Total | 44-38-1 | 262 | 1,755 | 29,868 | 26,500 | 43.0 | 53.9 | |||||||||||||
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More Bills Stats
Team Leaders 
PASS
1,039
Allen
RUSH
421
Cook
REC
270
Kincaid
Team Rankings
PPG
31.8
1st
OPP PPG
26.8
25th
RUSH YDS/G
139.0
5th
PASS YDS/G
259.8
9th
Jets
LAR
BAL
MIN
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 | |
| NFC North | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
| NFC South | W | L | T | PCT |
2 | 2 | 0 | .500 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
0 | 4 | 0 | .000 | |
| NFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 |
Giants
Eagles
Cowboys
Commanders
Bears
Lions
Packers
Panthers
Saints
Falcons
Buccaneers
49ers
Seahawks
Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 | |
0 | 4 | 0 | .000 | |
| AFC North | W | L | T | PCT |
3 | 1 | 0 | .750 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
| AFC South | W | L | T | PCT |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
0 | 4 | 0 | .000 | |
0 | 4 | 0 | .000 | |
| AFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
0 | 4 | 0 | .000 |
Titans