Since 2018, James Cook III has the most rushing yards for the Bills by a running back in a season, with 1,621 yards in 2025.
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| NAME | RUSH YDS | SEASON | TM | GP | ATT | YPC | RUSH YDS/G | RUSH TD | REC YDS | REC | TRG | AVG | REC YDS/G | REC TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Cook III | 1,621 | 2025 | 17 | 309 | 5.2 | 95.4 | 12 | 291 | 33 | 40 | 8.8 | 17.1 | 2 | |
| 2 | | J. Cook III | 1,122 | 2023 | 17 | 237 | 4.7 | 66.0 | 2 | 445 | 44 | 54 | 10.1 | 26.2 | 4 | |
| 3 | | J. Cook III | 1,009 | 2024 | 16 | 207 | 4.9 | 63.1 | 16 | 258 | 32 | 38 | 8.1 | 16.1 | 2 | |
| 4 |  | D. Singletary | 870 | 2021 | 17 | 188 | 4.6 | 51.2 | 7 | 228 | 40 | 50 | 5.7 | 13.4 | 1 | |
| 5 | | D. Singletary | 819 | 2022 | 16 | 177 | 4.6 | 51.2 | 5 | 280 | 38 | 52 | 7.4 | 17.5 | 1 | |
| 6 | | D. Singletary | 775 | 2019 | 12 | 151 | 5.1 | 64.6 | 2 | 194 | 29 | 41 | 6.7 | 16.2 | 2 | |
| 7 | | J. Cook III | 707 | 2026 | 7 | 138 | 5.1 | 101.0 | 7 | 110 | 12 | 17 | 9.2 | 15.7 | 0 | |
| 8 | | D. Singletary | 687 | 2020 | 16 | 156 | 4.4 | 42.9 | 2 | 269 | 38 | 50 | 7.1 | 16.8 | 0 | |
| 9 |  | F. Gore | 599 | 2019 | 16 | 166 | 3.6 | 37.4 | 2 | 100 | 13 | 16 | 7.7 | 6.3 | 0 | |
| 10 |  | L. McCoy | 514 | 2018 | 14 | 161 | 3.2 | 36.7 | 3 | 238 | 34 | 46 | 7.0 | 17.0 | 0 | |
| 11 | | J. Cook III | 507 | 2022 | 16 | 89 | 5.7 | 31.7 | 2 | 180 | 21 | 32 | 8.6 | 11.3 | 1 | |
| 12 |  | Z. Moss | 481 | 2020 | 13 | 112 | 4.3 | 37.0 | 4 | 95 | 14 | 18 | 6.8 | 7.3 | 1 | |
| 13 |  | R. Davis | 442 | 2024 | 17 | 113 | 3.9 | 26.0 | 3 | 189 | 17 | 19 | 11.1 | 11.1 | 3 | |
| 14 | | C. Ivory | 385 | 2018 | 13 | 115 | 3.3 | 29.6 | 1 | 205 | 13 | 21 | 15.8 | 15.8 | 0 | |
| 15 | | Z. Moss | 345 | 2021 | 13 | 96 | 3.6 | 26.5 | 4 | 197 | 23 | 32 | 8.6 | 15.2 | 1 | |
| 16 |  | L. Murray | 300 | 2023 | 16 | 79 | 3.8 | 18.8 | 4 | 119 | 17 | 22 | 7.0 | 7.4 | 0 | |
| 17 | | R. Davis | 275 | 2025 | 17 | 58 | 4.7 | 16.2 | 0 | 86 | 10 | 13 | 8.6 | 5.1 | 2 | |
| 18 | | M. Murphy | 250 | 2018 | 11 | 52 | 4.8 | 22.7 | 0 | 26 | 11 | 19 | 2.4 | 2.4 | 0 | |
| 19 | | T. Johnson | 213 | 2024 | 17 | 41 | 5.2 | 12.5 | 1 | 284 | 18 | 25 | 15.8 | 16.7 | 3 | |
| 20 | | T. Johnson | 200 | 2025 | 17 | 50 | 4.0 | 11.8 | 3 | 263 | 24 | 33 | 11.0 | 15.5 | 2 | |
| 21 | | T. Johnson | 132 | 2023 | 10 | 30 | 4.4 | 13.2 | 0 | 62 | 7 | 7 | 8.9 | 6.2 | 1 | |
| 22 |  | M. Breida | 125 | 2021 | 9 | 26 | 4.8 | 13.9 | 1 | 72 | 7 | 9 | 10.3 | 8.0 | 2 | |
| 23 |  | D. Harris | 94 | 2023 | 6 | 23 | 4.1 | 15.7 | 1 | 16 | 2 | 2 | 8.0 | 2.7 | 0 | |
| 24 | | Z. Moss | 91 | 2022 | 5 | 17 | 5.4 | 18.2 | 0 | 27 | 7 | 8 | 3.9 | 5.4 | 0 | |
| 25 | | K. Ford | 79 | 2018 | 2 | 21 | 3.8 | 39.5 | 0 | 21 | 3 | 5 | 7.0 | 10.5 | 0 | |
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More Bills Stats
Team Leaders 
PASS
1,793
Allen
RUSH
707
Cook
REC
401
Kincaid
Team Rankings
PPG
33.3
1st
OPP PPG
25.9
24th
RUSH YDS/G
148.4
3rd
PASS YDS/G
256.1
9th
Patriots
Jets
Dolphins
MIN
KC
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 2 | 1 | .643 | |
3 | 5 | 0 | .375 | |
2 | 4 | 1 | .357 | |
2 | 6 | 0 | .250 | |
| NFC North | W | L | T | PCT |
6 | 1 | 0 | .857 | |
6 | 2 | 0 | .750 | |
5 | 2 | 0 | .714 | |
5 | 3 | 0 | .625 | |
| NFC South | W | L | T | PCT |
3 | 4 | 0 | .429 | |
3 | 5 | 0 | .375 | |
3 | 5 | 0 | .375 | |
2 | 5 | 0 | .286 | |
| NFC West | W | L | T | PCT |
6 | 1 | 0 | .857 | |
4 | 4 | 0 | .500 | |
4 | 4 | 0 | .500 | |
3 | 5 | 0 | .375 |
Giants
Cowboys
Commanders
Eagles
Bears
Lions
Packers
Panthers
Buccaneers
Falcons
Saints
49ers
Seahawks
Rams
Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
6 | 1 | 0 | .857 | |
5 | 3 | 0 | .625 | |
2 | 6 | 0 | .250 | |
1 | 6 | 0 | .143 | |
| AFC North | W | L | T | PCT |
6 | 2 | 0 | .750 | |
5 | 2 | 0 | .714 | |
5 | 3 | 0 | .625 | |
4 | 4 | 0 | .500 | |
| AFC South | W | L | T | PCT |
5 | 2 | 0 | .714 | |
2 | 5 | 0 | .286 | |
2 | 6 | 0 | .250 | |
1 | 7 | 0 | .125 | |
| AFC West | W | L | T | PCT |
6 | 2 | 0 | .750 | |
5 | 2 | 0 | .714 | |
4 | 4 | 0 | .500 | |
0 | 7 | 0 | .000 |
Steelers
Bengals
Browns
Ravens
Jaguars
Texans
Colts
Titans
Broncos
Raiders
Chargers