The Buffalo Bills were 19-22-3 against the spread as underdogs against the AFC on the road from 2012 through 2021.

	TEAM	DATE	ATS	TM			OPP		RESULT	SPREAD	ATS DIFF	O/U	O/U DIFF	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	Bills	9/9/2012	0-1	BUF	+130	@	NYJ	-150	L 28-48	+3	-17 (N)	42.5	+33.5 (O)	4	20	390	384	66.7	100.0
2	Bills	11/4/2012	0-1	BUF	+450	@	HOU	-600	L 9-21	+11	-1 (N)	48	-18 (U)	0	17	304	374	18.2	100.0
3	Bills	11/11/2012	1-0	BUF	+600	@	NE	-800	L 31-37	+13.5	+7.5 (Y)	54	+14 (O)	4	35	481	347	63.6	100.0
4	Bills	11/25/2012	0-1	BUF	+115	@	IND	-135	L 13-20	+2	-5 (N)	51	-18 (U)	1	16	304	312	30.8
5	Bills	12/23/2012	0-1	BUF	+190	@	MIA	-235	L 10-24	+5	-9 (N)	43	-9 (U)	1	17	381	301	42.9	100.0
6	Bills	9/22/2013	0-1	BUF	+120	@	NYJ	-140	L 20-27	+2.5	-4.5 (N)	41	+6 (O)	1	18	328	513	22.2	0.0
7	Bills	10/3/2013	0-1	BUF	+170	@	CLE	-200	L 24-37	+3.5	-9.5 (N)	41	+20 (O)	3	20	343	290	31.3	50.0
8	Bills	10/20/2013	1-0	BUF	+220	@	MIA	-260	W 23-21	+6	+8 (Y)	44	0 (P)	2	15	268	293	47.4
9	Bills	11/10/2013	0-1	BUF	+130	@	PIT	-150	L 10-23	+3	-10 (N)	43	-10 (U)	1	16	227	300	21.4	100.0
10	Bills	12/29/2013	0-1	BUF	+280	@	NE	-350	L 20-34	+7.5	-6.5 (N)	46.5	+7.5 (O)	2	19	393	382	30.8	0.0
11	Bills	9/28/2014	0-1	BUF	+130	@	HOU	-150	L 17-23	+3	-3 (N)	44	-4 (U)	2	17	316	301	31.3
12	Bills	10/26/2014	1-0	BUF	+130	@	NYJ	-150	W 43-23	+3	+23 (Y)	40.5	+25.5 (O)	5	12	280	312	25.0
13	Bills	11/13/2014	0-1	BUF	+175	@	MIA	-210	L 9-22	+3.5	-9.5 (N)	41.5	-10.5 (U)	0	13	237	330	40.0	0.0
14	Bills	12/7/2014	1-0	BUF	+350	@	DEN	-425	L 17-24	+9	+2 (Y)	47	-6 (U)	2	24	415	306	56.3	66.7
15	Bills	12/28/2014	1-0	BUF	+175	@	NE	-210	W 17-9	+4	+12 (Y)	44	-18 (U)	2	16	268	260	45.5
16	Bills	9/27/2015	1-0	BUF	+105	@	MIA	-125	W 41-14	+2	+29 (Y)	44	+11 (O)	5	21	428	391	53.8
17	Bills	11/12/2015	1-0	BUF	+115	@	NYJ	-135	W 22-17	+2	+7 (Y)	42	-3 (U)	2	13	280	318	31.3	0.0
18	Bills	11/23/2015	0-0-1	BUF	+290	@	NE	-350	L 13-20	+7	0 (P)	48	-15 (U)	1	16	319	356	20.0	100.0
19	Bills	11/29/2015	0-1	BUF	+185	@	KC	-215	L 22-30	+4	-4 (N)	41	+11 (O)	3	25	415	413	41.7	0.0
20	Bills	9/11/2016	0-1	BUF	+130	@	BAL	-150	L 7-13	+3	-3 (N)	45	-25 (U)	1	11	160	308	23.1	100.0
21	Bills	10/2/2016	1-0	BUF	+165	@	NE	-200	W 16-0	+3.5	+19.5 (Y)	41	-25 (U)	1	24	378	277	46.7
22	Bills	11/20/2016	1-0	BUF	+120	@	CIN	-140	W 16-12	+2.5	+6.5 (Y)	48	-20 (U)	1	20	342	300	25.0	100.0
23	Bills	12/4/2016	0-1	BUF	+145	@	OAK	-165	L 24-38	+3	-11 (N)	48.5	+13.5 (O)	3	24	382	399	60.0
24	Bills	10/8/2017	0-1	BUF	+140	@	CIN	-150	L 16-20	+3	-1 (N)	39.5	-3.5 (U)	1	17	221	388	33.3
25	Bills	11/19/2017	0-1	BUF	+270	@	LAC	-300	L 24-54	+7	-23 (N)	41.5	+36.5 (O)	3	18	393	429	42.9	50.0
	Average		1.1											2.0	18.8	331.4	334.2	37.8	0.0
	Total		19-22-3											89	827	14,580	14,703	37.8	51.9

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More Bills Stats

Team Leaders

PASS

1,039

Allen

RUSH

421

Cook

REC

270

Kincaid

Team Rankings

PPG

31.8

1st

OPP PPG

26.8

25th

RUSH YDS/G

139.0

5th

PASS YDS/G

259.8

9th

2026 Division Standings

TEAM	W	L	PCT
Bills	3	1	.750
Patriots	2	2	.500
Jets	1	3	.250
Dolphins	0	4	.000

Schedule

DATE	MATCHUP			TIME (ET)
Mon 10/12	BUF	@	LAR	8:15 PM
Sun 10/18	BUF	@	LV	4:25 PM
Sun 11/1	BAL	@	BUF	1:00 PM
Mon 11/9	BUF	@	MIN	8:15 PM
Sun 11/15	BUF	@	NYJ	1:00 PM

Last Game

Patriots

2 - 2

Final

Bills

3 - 1

Sun 4 Oct 2026

NFL 2026 Leaders

Pass Yards Leaders

1,268

Young

1,214

Goff

1,203

Shough

Rush Yards Leaders

537

Walker

494

Robinson

421

Cook

Rec Yards Leaders

498

Lamb

491

Olave

481

Smith-Njigba

Pass TD Leaders

11

Purdy

11

Cousins

9

Shough

Rush TD Leaders

7

Allen

7

Henry

6

Taylor

Rec TD Leaders

6

Smith-Njigba

5

St. Brown

4

Watson

QB Rating Leaders

126.2

Purdy

119.6

Jackson

111.2

Lawrence

Sack Leaders

6.0

Rousseau

5.5

Turner

4.5

Anderson

NFL 2026 Rankings

PPG Rankings

31.8

30.5

30.3

29.8

29.5

Opp PPG Rankings

12.8

13.3

16.0

16.3

18.3

19.3

Total Yards Rankings

429.0

417.0

412.0

405.8

395.0

389.3

Rush Yards Rankings

196.3

181.0

162.3

153.5

139.0

137.3

Pass Yards Rankings

317.0

303.5

300.8

300.5

292.8

285.3

Sack Leaders

16.0

15.0

14.0

12.0

NFL Fantasy 2026

Fantasy RB Rankings

98.1

Walker

94

Gibbs

91.4

Robinson

Fantasy WR Rankings

84.7

Smith-Njigba

75.2

Lamb

60.3

St. Brown

Fantasy TE Rankings

48.4

Kittle

39.2

Johnson

36.6

Kelce

Fantasy K Rankings

54

Shrader

52

Reichard

47

McPherson

NFL 2026 Betting

Best Record ATS

4-0

3-1

Worst Record ATS

0-4

0-3-1

1-3

NFL 2026 Standings

NFC East	W	L	T	PCT
Giants	3	1	0	.750
Eagles	2	2	0	.500
Cowboys	2	2	0	.500
Commanders	1	3	0	.250
NFC North	W	L	T	PCT
Vikings	4	0	0	1.000
Bears	3	1	0	.750
Lions	2	2	0	.500
Packers	2	2	0	.500
NFC South	W	L	T	PCT
Panthers	2	2	0	.500
Falcons	2	2	0	.500
Saints	1	3	0	.250
Buccaneers	0	4	0	.000
NFC West	W	L	T	PCT
49ers	4	0	0	1.000
Seahawks	3	1	0	.750
Rams	2	2	0	.500
Cardinals	1	3	0	.250

AFC East	W	L	T	PCT
Bills	3	1	0	.750
Patriots	2	2	0	.500
Jets	1	3	0	.250
Dolphins	0	4	0	.000
AFC North	W	L	T	PCT
Browns	3	1	0	.750
Ravens	3	1	0	.750
Steelers	2	2	0	.500
Bengals	2	2	0	.500
AFC South	W	L	T	PCT
Jaguars	3	1	0	.750
Colts	2	2	0	.500
Titans	0	4	0	.000
Texans	0	4	0	.000
AFC West	W	L	T	PCT
Chiefs	4	0	0	1.000
Raiders	3	1	0	.750
Broncos	2	2	0	.500
Chargers	0	4	0	.000

NFL 2026 Scores & Schedule

Scores

DATE	MATCHUP			SCORE
Wed 9/9	NE	@	SEA	10-13
Thu 9/10	SF	@	LAR	27-7
Sun 9/13	CHI	@	CAR	59-37
Sun 9/13	BAL	@	IND	41-23
Sun 9/13	ATL	@	PIT	13-20

Schedule

DATE	MATCHUP			TIME (ET)
Thu 10/8	TB	@	DAL	8:15 PM
Sun 10/11	PHI	@	JAX	9:30 AM
Sun 10/11	CLE	@	NYJ	1:00 PM
Sun 10/11	CIN	@	MIA	1:00 PM
Sun 10/11	LV	@	NE	1:00 PM

The Buffalo Bills were 19-22-3 against the spread as underdogs against the AFC on the road from 2012 through 2021.

Related Searches

More NFL News

More Bills Stats

1,039

421

270

NFL 2026 Leaders

1,268

1,214

1,203

537

494

421

498

491

481

11

11

9

7

7

6

6

5

4

126.2

119.6

111.2

6.0

5.5

4.5

NFL 2026 Rankings

NFL Fantasy 2026

98.1

94

91.4

84.7

75.2

60.3

48.4

39.2

36.6

54

52

47

NFL 2026 Betting

NFL 2026 Standings

NFL 2026 Scores & Schedule

Scores

Schedule