| TEAM | OPPONENT | WEEK/ROUND | DATE | TIME (ET) | SPREAD | OVER/UNDER | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Buffalo Bills | -225 | vs | +187 | WK 3 | Sun, Sep 27, 2026 | 1:00 PM | -4.5 | 50.5 | |
| 2 | | Buffalo Bills | -200 | vs | +160 | WK 4 | Sun, Oct 4, 2026 | 1:00 PM | -4.0 | 50.5 | |
| 3 | | Buffalo Bills | +160 | @ | -191 | WK 5 | Mon, Oct 12, 2026 | 8:15 PM | +3.5 | 54.5 | |
| 4 | | Buffalo Bills | -355 | @ | +260 | WK 6 | Sun, Oct 18, 2026 | 4:25 PM | -7.0 | 48.5 | |
| 5 | | Buffalo Bills | -178 | vs | +150 | WK 12 | Thu, Nov 26, 2026 | 8:20 PM | -3.0 | 51.5 | |
| 6 | | Buffalo Bills | -116 | @ | -106 | WK 16 | Fri, Dec 25, 2026 | 4:30 PM | -1.0 | 47.5 |
Los Angeles Chargers
New England Patriots
Los Angeles Rams
Las Vegas Raiders
Kansas City Chiefs
Denver BroncosBetting lines shown represent consensus, closing odds.
More NFL News
Two-time All-Pro cornerback Stephon Gilmore retires as member of Patriots
Josh Allen opens the Bills' new stadium with a 5-TD outing in a 41-31 win over the Lions
With mentors like Christan McCaffrey and Matthew McConaughey, Bijan Robinson just gets better
Fireworks, 2 anthems and a full house: Bills beat Lions in 1st regular-season game at new stadium
Bengals hope strong defensive line play from opener continues at Houston
Jefferson opened the season with a return to the end zone, rewarding the Vikings for the opportunity
More Bills Stats
Team Leaders 
PASS
582
Allen
RUSH
192
Cook
REC
225
Kincaid
Team Rankings
PPG
38.5
4th
OPP PPG
31.0
22nd
RUSH YDS/G
144.5
7th
PASS YDS/G
291.0
5th
Bills
Jets
Dolphins
BAL
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
0 | 1 | 0 | .000 | |
| NFC South | W | L | T | PCT |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 |
Giants
Eagles
Commanders
Cowboys
Vikings
Bears
Lions
Packers
Falcons
Buccaneers
Panthers
Saints
49ers
Cardinals
Seahawks| AFC East | W | L | T | PCT |
|---|---|---|---|---|
2 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
| AFC South | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 |
Bengals
Steelers
Browns
Jaguars
Texans
Titans
Colts