The Buffalo Bills have 4,560 yards of total offense against the Lions with >0 yards of total offense all-time.
| TEAM | DATE | OFF | TM | OPP | RESULT | TD | 1DWN | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 12/10/1972 | 418 | vs | T 21-21 | 3 | 23 | 260 | ||||
| 2 | | Bills | 11/25/1976 | 322 | @ | L 14-27 | 2 | 19 | 304 | ||||
| 3 | | Bills | 10/28/1979 | 424 | @ | W 20-17 | 2 | 18 | 377 | ||||
| 4 | | Bills | 12/22/1991 | 275 | vs | L 14-17 | 2 | 14 | 356 | 25.0 | 0.0 | ||
| 5 | | Bills | 11/24/1994 | 367 | @ | L 21-35 | 3 | 25 | 388 | 50.0 | 100.0 | ||
| 6 | | Bills | 10/5/1997 | 266 | vs | W 22-13 | 2 | 10 | 309 | 18.2 | |||
| 7 | | Bills | 10/27/2002 | 343 | vs | W 24-17 | 3 | 23 | 282 | 42.9 | 100.0 | ||
| 8 | | Bills | 10/15/2006 | 242 | @ | L 17-20 | 2 | 16 | 397 | 27.3 | |||
| 9 | | Bills | 11/14/2010 | 288 | vs | W 14-12 | 2 | 12 | 390 | 33.3 | 0.0 | ||
| 10 | | Bills | 10/5/2014 | 343 | @ | W 17-14 | 1 | 19 | 273 | 31.3 | |||
| 11 | | Bills | 12/16/2018 | 312 | vs | W 14-13 | 2 | 20 | 313 | 25.0 | 50.0 | ||
| 12 | | Bills | 11/24/2022 | 401 | @ | W 28-25 | 3 | 28 | 326 | 58.3 | |||
| 13 | | Bills | 12/15/2024 | 559 | @ | W 48-42 | 6 | 28 | 521 | 50.0 | 100.0 | ||
| Average | 350.8 | 2.5 | 19.6 | 345.8 | 0.1 | ||||||||
| Total | 4,560 | 33 | 255 | 4,496 | 57.1 |
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More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |