The Arizona Cardinals have a 22-29 record against the 49ers between October 5, 1996 and October 5, 2026.
| TEAM | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cardinals | 9/27/1999 | vs | L 10-24 | 1 | 20 | 250 | 322 | 30.8 | 100.0 | ||
| 2 | | Cardinals | 10/1/2000 | @ | L 20-27 | 2 | 16 | 365 | 345 | 23.1 | 66.7 | ||
| 3 | | Cardinals | 10/27/2002 | @ | L 28-38 | 4 | 23 | 420 | 357 | 75.0 | 100.0 | ||
| 4 | | Cardinals | 12/21/2002 | vs | L 14-17 | 2 | 14 | 184 | 358 | 53.8 | |||
| 5 | | Cardinals | 10/26/2003 | vs | W 16-13 | 1 | 18 | 314 | 255 | 40.0 | |||
| 6 | | Cardinals | 12/7/2003 | @ | L 14-50 | 2 | 18 | 210 | 496 | 21.4 | 66.7 | ||
| 7 | | Cardinals | 10/10/2004 | @ | L 28-31 | 4 | 19 | 320 | 448 | 35.7 | 100.0 | ||
| 8 | | Cardinals | 12/12/2004 | vs | L 28-31 | 3 | 25 | 374 | 352 | 43.8 | |||
| 9 | | Cardinals | 10/2/2005 | vs | W 31-14 | 2 | 24 | 463 | 168 | 42.1 | |||
| 10 | | Cardinals | 12/4/2005 | @ | W 17-10 | 1 | 18 | 404 | 220 | 31.3 | 0.0 | ||
| 11 | | Cardinals | 9/10/2006 | vs | W 34-27 | 4 | 23 | 367 | 393 | 50.0 | |||
| 12 | | Cardinals | 12/24/2006 | @ | W 26-20 | 2 | 21 | 372 | 223 | 50.0 | 100.0 | ||
| 13 | | Cardinals | 9/10/2007 | @ | L 17-20 | 2 | 20 | 261 | 194 | 40.0 | |||
| 14 | | Cardinals | 11/25/2007 | vs | L 31-37 | 4 | 25 | 552 | 374 | 28.6 | 100.0 | ||
| 15 | | Cardinals | 9/7/2008 | @ | W 23-13 | 2 | 18 | 285 | 291 | 31.3 | 66.7 | ||
| 16 | | Cardinals | 11/10/2008 | vs | W 29-24 | 3 | 21 | 374 | 336 | 30.8 | 100.0 | ||
| 17 | | Cardinals | 9/13/2009 | vs | L 16-20 | 1 | 17 | 299 | 203 | 28.6 | 0.0 | ||
| 18 | | Cardinals | 12/14/2009 | @ | L 9-24 | 1 | 11 | 245 | 327 | 36.4 | 100.0 | ||
| 19 | | Cardinals | 11/29/2010 | vs | L 6-27 | 0 | 8 | 203 | 386 | 18.2 | 0.0 | ||
| 20 | | Cardinals | 1/2/2011 | @ | L 7-38 | 1 | 19 | 279 | 362 | 45.0 | 0.0 | ||
| 21 | | Cardinals | 11/20/2011 | @ | L 7-23 | 1 | 11 | 229 | 431 | 11.1 | 0.0 | ||
| 22 | | Cardinals | 12/11/2011 | vs | W 21-19 | 3 | 12 | 325 | 233 | 21.4 | |||
| 23 | | Cardinals | 10/29/2012 | vs | L 3-24 | 0 | 16 | 265 | 317 | 14.3 | 50.0 | ||
| 24 | | Cardinals | 12/30/2012 | @ | L 13-27 | 1 | 11 | 262 | 407 | 25.0 | 100.0 | ||
| 25 | | Cardinals | 10/13/2013 | @ | L 20-32 | 3 | 16 | 403 | 387 | 38.5 | 0.0 | ||
| Average | 2.3 | 19.7 | 340.8 | 341.1 | 37.7 | 0.0 | |||||||
| Total | 118 | 1,003 | 17,382 | 17,396 | 37.7 | 61.5 | |||||||
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More Cardinals Stats
Team Leaders 
PASS
818
Brissett
RUSH
223
Love
REC
258
Wilson
Team Rankings
PPG
21.8
16th
OPP PPG
29.3
30th
RUSH YDS/G
100.5
22nd
PASS YDS/G
204.5
22nd
Seahawks
Rams
DET
DEN
DAL
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 | |
| NFC North | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
| NFC South | W | L | T | PCT |
2 | 2 | 0 | .500 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
0 | 4 | 0 | .000 | |
| NFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 |
Giants
Eagles
Commanders
Vikings
Bears
Packers
Panthers
Saints
Falcons
Buccaneers| AFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 | |
0 | 4 | 0 | .000 | |
| AFC North | W | L | T | PCT |
3 | 1 | 0 | .750 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
| AFC South | W | L | T | PCT |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
0 | 4 | 0 | .000 | |
0 | 4 | 0 | .000 | |
| AFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
0 | 4 | 0 | .000 |
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