The Los Angeles Chargers had a record of 5-6 against the spread as favorites against the AFC East at home from 2010 through 2021.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Chargers | 10/24/2010 | 0-1 | -135 | vs | +115 | L 20-23 | -2.5 | -5.5 (N) | 48.5 | -5.5 (U) | 2 | 23 | 363 | 179 | 46.7 | 100.0 | ||
| 2 | | Chargers | 10/2/2011 | 1-0 | -300 | vs | +250 | W 26-16 | -7 | +3 (Y) | 45 | -3 (U) | 2 | 21 | 411 | 248 | 50.0 | |||
| 3 | | Chargers | 12/11/2011 | 1-0 | -340 | vs | +280 | W 37-10 | -7 | +20 (Y) | 48.5 | -1.5 (U) | 5 | 23 | 366 | 281 | 57.1 | 100.0 | ||
| 4 | | Chargers | 10/5/2014 | 1-0 | -305 | vs | +255 | W 31-0 | -6.5 | +24.5 (Y) | 44 | -13 (U) | 4 | 21 | 439 | 151 | 66.7 | |||
| 5 | | Chargers | 12/20/2015 | 1-0 | -120 | vs | +100 | W 30-14 | -1 | +15 (Y) | 46.5 | -2.5 (U) | 4 | 26 | 442 | 231 | 64.3 | |||
| 6 | | Chargers | 11/13/2016 | 0-1 | -210 | vs | +180 | L 24-31 | -4.5 | -11.5 (N) | 49 | +6 (O) | 3 | 29 | 379 | 337 | 54.5 | |||
| 7 | | Chargers | 9/17/2017 | 0-1 | -178 | vs | +167 | L 17-19 | -3.5 | -5.5 (N) | 46.5 | -10.5 (U) | 2 | 24 | 367 | 336 | 25.0 | |||
| 8 | | Chargers | 11/19/2017 | 1-0 | -300 | vs | +270 | W 54-24 | -7 | +23 (Y) | 41.5 | +36.5 (O) | 6 | 28 | 429 | 393 | 50.0 | |||
| 9 | | Chargers | 11/22/2020 | 0-1 | -453 | vs | +355 | W 34-28 | -9.5 | -3.5 (N) | 47 | +15 (O) | 4 | 28 | 376 | 292 | 60.0 | 0.0 | ||
| 10 | | Chargers | 12/6/2020 | 0-1 | -138 | vs | +117 | L 0-45 | -2 | -47 (N) | 46.5 | -1.5 (U) | 0 | 17 | 258 | 291 | 38.9 | 20.0 | ||
| 11 | | Chargers | 10/31/2021 | 0-1 | -191 | vs | +160 | L 24-27 | -3.5 | -6.5 (N) | 50.5 | +0.5 (O) | 3 | 17 | 369 | 352 | 33.3 | 100.0 | ||
| Average | 4.1 | 3.2 | 23.4 | 381.7 | 281.0 | 51.0 | 0.1 | |||||||||||||
| Total | 5-6 | 35 | 257 | 4,199 | 3,091 | 51.0 | 44.4 |
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Team Leaders 
PASS
937
Herbert
RUSH
271
Hampton
REC
225
Harris
Team Rankings
PPG
16.8
30th
OPP PPG
25.8
22nd
RUSH YDS/G
128.2
9th
PASS YDS/G
187.4
28th
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| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 1 | .700 | |
2 | 3 | 0 | .400 | |
2 | 3 | 0 | .400 | |
1 | 3 | 1 | .300 | |
| NFC North | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
| NFC South | W | L | T | PCT |
2 | 2 | 0 | .500 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 | |
1 | 4 | 0 | .200 | |
| NFC West | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
3 | 3 | 0 | .500 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 |
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Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 1 | 0 | .800 | |
3 | 2 | 0 | .600 | |
2 | 3 | 0 | .400 | |
0 | 5 | 0 | .000 | |
| AFC North | W | L | T | PCT |
4 | 1 | 0 | .800 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
| AFC South | W | L | T | PCT |
4 | 1 | 0 | .800 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 | |
0 | 5 | 0 | .000 | |
| AFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
4 | 2 | 0 | .667 | |
3 | 2 | 0 | .600 | |
0 | 5 | 0 | .000 |
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