| NAME | DATE | GP | TM | OPP | CMP | ATT | PCT | YDS | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | B. Mayfield | 1/3/2026 | 1 | vs | 16 | 22 | 72.7 | 203 | 9.2 | 1 | 1 | 97.3 | 4.5 | 4.5 | 2 | 5 | ||
| 2 | | B. Mayfield | 12/28/2025 | 1 | @ | 33 | 44 | 75.0 | 346 | 7.9 | 2 | 2 | 93.6 | 4.5 | 4.5 | 3 | 19 | ||
| 3 | | B. Mayfield | 12/21/2025 | 1 | @ | 18 | 26 | 69.2 | 145 | 5.6 | 1 | 1 | 79.8 | 3.8 | 3.8 | 2 | 18 | ||
| 4 | | B. Mayfield | 12/11/2025 | 1 | vs | 19 | 34 | 55.9 | 277 | 8.1 | 2 | 1 | 90.0 | 5.9 | 2.9 | 5 | 27 | ||
| 5 | | B. Mayfield | 12/7/2025 | 1 | vs | 14 | 30 | 46.7 | 122 | 4.1 | 1 | 1 | 55.1 | 3.3 | 3.3 | 0 | 0 | ||
| 6 | | B. Mayfield | 11/30/2025 | 1 | vs | 18 | 28 | 64.3 | 194 | 6.9 | 1 | 0 | 96.4 | 3.6 | 0.0 | 2 | 10 | ||
| 7 | | B. Mayfield | 11/23/2025 | 1 | @ | 9 | 19 | 47.4 | 41 | 2.2 | 1 | 2 | 32.0 | 5.3 | 10.5 | 2 | 12 | ||
| 8 | | B. Mayfield | 11/16/2025 | 1 | @ | 16 | 28 | 57.1 | 173 | 6.2 | 1 | 1 | 72.5 | 3.6 | 3.6 | 1 | 8 | ||
| 9 | | B. Mayfield | 11/9/2025 | 1 | vs | 28 | 43 | 65.1 | 273 | 6.3 | 3 | 0 | 106.1 | 7.0 | 0.0 | 2 | 15 | ||
| 10 | | B. Mayfield | 10/26/2025 | 1 | @ | 15 | 24 | 62.5 | 152 | 6.3 | 0 | 0 | 80.6 | 0.0 | 0.0 | 3 | 28 | ||
| 11 | | B. Mayfield | 10/20/2025 | 1 | @ | 28 | 50 | 56.0 | 228 | 4.6 | 1 | 1 | 66.1 | 2.0 | 2.0 | 4 | 18 | ||
| 12 | | B. Mayfield | 10/12/2025 | 1 | vs | 17 | 23 | 73.9 | 256 | 11.1 | 2 | 0 | 139.0 | 8.7 | 0.0 | 1 | 8 | ||
| 13 | | B. Mayfield | 10/5/2025 | 1 | @ | 29 | 33 | 87.9 | 379 | 11.5 | 2 | 0 | 134.7 | 6.1 | 0.0 | 1 | 9 | ||
| 14 | | B. Mayfield | 9/28/2025 | 1 | vs | 22 | 40 | 55.0 | 289 | 7.2 | 2 | 1 | 84.3 | 5.0 | 2.5 | 2 | 17 | ||
| 15 | | B. Mayfield | 9/21/2025 | 1 | vs | 19 | 29 | 65.5 | 233 | 8.0 | 1 | 0 | 101.7 | 3.4 | 0.0 | 1 | 8 | ||
| 16 | | B. Mayfield | 9/15/2025 | 1 | @ | 25 | 38 | 65.8 | 215 | 5.7 | 2 | 0 | 98.0 | 5.3 | 0.0 | 4 | 24 | ||
| 17 | | B. Mayfield | 9/7/2025 | 1 | @ | 17 | 32 | 53.1 | 167 | 5.2 | 3 | 0 | 99.3 | 9.4 | 0.0 | 1 | 8 | ||
| 18 | | B. Mayfield | 1/5/2025 | 1 | vs | 21 | 32 | 65.6 | 221 | 6.9 | 2 | 1 | 93.4 | 6.3 | 3.1 | 1 | 5 | ||
| 19 | | B. Mayfield | 12/29/2024 | 1 | vs | 27 | 32 | 84.4 | 359 | 11.2 | 5 | 0 | 153.0 | 15.6 | 0.0 | 2 | 10 | ||
| 20 | | B. Mayfield | 12/22/2024 | 1 | @ | 31 | 43 | 72.1 | 303 | 7.0 | 2 | 1 | 97.3 | 4.7 | 2.3 | 4 | 27 | ||
| 21 | | B. Mayfield | 12/15/2024 | 1 | @ | 22 | 27 | 81.5 | 288 | 10.7 | 4 | 1 | 135.3 | 14.8 | 3.7 | 1 | 5 | ||
| 22 | | B. Mayfield | 12/8/2024 | 1 | vs | 18 | 29 | 62.1 | 295 | 10.2 | 3 | 2 | 101.9 | 10.3 | 6.9 | 4 | 27 | ||
| 23 | | B. Mayfield | 12/1/2024 | 1 | @ | 21 | 33 | 63.6 | 235 | 7.1 | 1 | 2 | 69.6 | 3.0 | 6.1 | 4 | 31 | ||
| 24 | | B. Mayfield | 11/24/2024 | 1 | @ | 24 | 30 | 80.0 | 294 | 9.8 | 0 | 0 | 107.5 | 0.0 | 0.0 | 0 | 0 | ||
| 25 | | B. Mayfield | 11/10/2024 | 1 | vs | 18 | 29 | 62.1 | 116 | 4.0 | 1 | 0 | 82.0 | 3.4 | 0.0 | 2 | 11 | ||
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| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |