The San Francisco 49ers had the highest point differential by a team in a Week-18 game in 2022, with a 25-point differential against the Cardinals on January 8, 2023.
| TEAM | DIFF | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 25 | 1/8/2023 | vs | W 38-13 | 5 | 21 | 311 | 255 | 46.2 | 0.0 | ||
| 2 |  | Commanders | 20 | 1/8/2023 | vs | W 26-6 | 3 | 16 | 309 | 182 | 21.4 | |||
| 3 |  | Chiefs | 18 | 1/7/2023 | @ | W 31-13 | 4 | 21 | 349 | 279 | 55.6 | |||
| 4 |  | Vikings | 16 | 1/8/2023 | @ | W 29-13 | 3 | 28 | 482 | 259 | 54.5 | |||
| 5 |  | Steelers | 14 | 1/8/2023 | vs | W 28-14 | 3 | 23 | 333 | 307 | 60.0 | |||
| 6 |  | Falcons | 13 | 1/8/2023 | vs | W 30-17 | 3 | 22 | 382 | 222 | 40.0 | 100.0 | ||
| 7 |  | Bills | 12 | 1/8/2023 | vs | W 35-23 | 5 | 18 | 327 | 341 | 58.3 | |||
| 8 |  | Bengals | 11 | 1/8/2023 | vs | W 27-16 | 3 | 15 | 257 | 386 | 33.3 | 0.0 | ||
| 9 |  | Eagles | 6 | 1/8/2023 | vs | W 22-16 | 1 | 23 | 342 | 284 | 35.7 | |||
| 10 |  | Dolphins | 5 | 1/8/2023 | vs | W 11-6 | 0 | 17 | 302 | 187 | 30.8 | 50.0 | ||
| 11 |  | Lions | 4 | 1/8/2023 | @ | W 20-16 | 2 | 21 | 323 | 291 | 33.3 | 100.0 | ||
| 12 |  | Jaguars | 4 | 1/7/2023 | vs | W 20-16 | 2 | 13 | 222 | 312 | 45.5 | |||
| 13 |  | Panthers | 3 | 1/8/2023 | @ | W 10-7 | 1 | 14 | 203 | 304 | 57.1 | |||
| 14 |  | Broncos | 3 | 1/8/2023 | vs | W 31-28 | 4 | 22 | 471 | 352 | 41.7 | 100.0 | ||
| 15 |  | Seahawks | 3 | 1/8/2023 | vs | W 19-16 | 1 | 22 | 402 | 269 | 9.1 | 100.0 | ||
| 16 |  | Texans | 1 | 1/8/2023 | @ | W 32-31 | 4 | 18 | 360 | 398 | 35.7 | 100.0 | ||
| 17 |  | Colts | -1 | 1/8/2023 | vs | L 31-32 | 4 | 25 | 398 | 360 | 30.8 | 66.7 | ||
| 18 |  | Saints | -3 | 1/8/2023 | vs | L 7-10 | 1 | 16 | 304 | 203 | 30.8 | 0.0 | ||
| 19 |  | Chargers | -3 | 1/8/2023 | @ | L 28-31 | 3 | 21 | 352 | 471 | 50.0 | |||
| 20 |  | Rams | -3 | 1/8/2023 | @ | L 16-19 | 1 | 14 | 269 | 402 | 28.6 | 100.0 | ||
| 21 |  | Packers | -4 | 1/8/2023 | vs | L 16-20 | 1 | 17 | 291 | 323 | 33.3 | 50.0 | ||
| 22 |  | Titans | -4 | 1/7/2023 | @ | L 16-20 | 1 | 19 | 312 | 222 | 35.3 | 66.7 | ||
| 23 |  | Jets | -5 | 1/8/2023 | @ | L 6-11 | 0 | 11 | 187 | 302 | 43.8 | |||
| 24 |  | Giants | -6 | 1/8/2023 | @ | L 16-22 | 2 | 18 | 284 | 342 | 28.6 | 66.7 | ||
| 25 |  | Ravens | -11 | 1/8/2023 | @ | L 16-27 | 1 | 20 | 386 | 257 | 37.5 | 0.0 | ||
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More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |