Patrick Mahomes had his most passing yards in a game in 2021 against the Chargers on December 16, 2021, with 410 yards.
Interpreted as:
highest passing yards in a regular-season game 2021 mahomes| NAME | YDS | DATE | TM | OPP | CMP | ATT | PCT | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | P. Mahomes | 410 | 12/16/2021 | @ | 31 | 47 | 66.0 | 8.7 | 3 | 1 | 105.8 | 6.4 | 2.1 | 1 | 0 | ||
| 2 | | P. Mahomes | 406 | 11/14/2021 | @ | 35 | 50 | 70.0 | 8.1 | 5 | 0 | 127.6 | 10.0 | 0.0 | 0 | 0 | ||
| 3 | | P. Mahomes | 397 | 10/17/2021 | @ | 32 | 47 | 68.1 | 8.4 | 2 | 2 | 90.5 | 4.3 | 4.3 | 3 | 7 | ||
| 4 | | P. Mahomes | 343 | 9/19/2021 | @ | 24 | 31 | 77.4 | 11.1 | 3 | 1 | 131.5 | 9.7 | 3.2 | 0 | 0 | ||
| 5 | | P. Mahomes | 337 | 9/12/2021 | vs | 27 | 36 | 75.0 | 9.4 | 3 | 0 | 131.4 | 8.3 | 0.0 | 2 | 13 | ||
| 6 | | P. Mahomes | 278 | 10/3/2021 | @ | 24 | 30 | 80.0 | 9.3 | 5 | 1 | 131.0 | 16.7 | 3.3 | 1 | 7 | ||
| 7 | | P. Mahomes | 275 | 11/1/2021 | vs | 29 | 48 | 60.4 | 5.7 | 1 | 1 | 74.6 | 2.1 | 2.1 | 2 | 14 | ||
| 8 | | P. Mahomes | 272 | 10/10/2021 | vs | 33 | 54 | 61.1 | 5.0 | 2 | 2 | 70.9 | 3.7 | 3.7 | 2 | 0 | ||
| 9 | | P. Mahomes | 270 | 1/8/2022 | @ | 27 | 44 | 61.4 | 6.1 | 2 | 0 | 93.9 | 4.5 | 0.0 | 1 | 15 | ||
| 10 | | P. Mahomes | 260 | 11/21/2021 | vs | 23 | 37 | 62.2 | 7.0 | 0 | 1 | 71.9 | 0.0 | 2.7 | 3 | 16 | ||
| 11 | | P. Mahomes | 260 | 9/26/2021 | vs | 27 | 44 | 61.4 | 5.9 | 3 | 2 | 81.6 | 6.8 | 4.5 | 2 | 9 | ||
| 12 | | P. Mahomes | 259 | 1/2/2022 | @ | 26 | 35 | 74.3 | 7.4 | 2 | 0 | 113.9 | 5.7 | 0.0 | 0 | 0 | ||
| 13 | | P. Mahomes | 258 | 12/26/2021 | vs | 23 | 30 | 76.7 | 8.6 | 3 | 0 | 135.1 | 10.0 | 0.0 | 2 | 4 | ||
| 14 | | P. Mahomes | 258 | 12/12/2021 | vs | 20 | 24 | 83.3 | 10.8 | 2 | 0 | 139.2 | 8.3 | 0.0 | 3 | 18 | ||
| 15 | | P. Mahomes | 206 | 10/24/2021 | @ | 20 | 35 | 57.1 | 5.9 | 0 | 1 | 62.3 | 0.0 | 2.9 | 4 | 31 | ||
| 16 | | P. Mahomes | 184 | 12/5/2021 | vs | 15 | 29 | 51.7 | 6.3 | 0 | 1 | 57.3 | 0.0 | 3.4 | 1 | 6 | ||
| 17 | | P. Mahomes | 166 | 11/7/2021 | vs | 20 | 37 | 54.1 | 4.5 | 1 | 0 | 74.8 | 2.7 | 0.0 | 1 | 6 |
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More Chiefs Stats
Team Leaders 
PASS
3,587
Mahomes
RUSH
611
Hunt
REC
851
Kelce
Team Rankings
PPG
21.3
21st
OPP PPG
19.3
6th
RUSH YDS/G
106.6
25th
PASS YDS/G
232.2
16th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |