Between the 1980 and 1989 seasons, Ronnie Lott caught the most interceptions, with 48 interceptions.
Interpreted as:
defensive interception leaders 1980s| NAME | INT | GP | TKL | AST | COMB | SCK | SCKY | INT YDS | INT TD | FF | FR | FR TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Lott | 48 | 118 | 5.5 | 617 | 5 | 11 | 0 | |||||
| 2 |  | D. Brown | 46 | 143 | 0.0 | 470 | 4 | 9 | 0 | |||||
| 3 | | E. Walls | 44 | 133 | 1.0 | 391 | 0 | 3 | 0 | |||||
| 4 | | J. Harris | 44 | 130 | 1.0 | 465 | 2 | 11 | 0 | |||||
| 5 | | D. Cherry | 43 | 123 | 3.5 | 617 | 1 | 13 | 0 | |||||
| 6 | | D. Shell | 37 | 115 | 1.0 | 412 | 2 | 8 | 1 | |||||
| 7 | | D. Waymer | 37 | 149 | 0.0 | 395 | 0 | 15 | 0 | |||||
| 8 | | M. Downs | 35 | 121 | 8.0 | 470 | 1 | 14 | 2 | |||||
| 9 | | M. Harden | 35 | 143 | 1.0 | 644 | 4 | 14 | 0 | |||||
| 10 | | L. Irvin | 34 | 143 | 1.5 | 654 | 5 | 13 | 1 | |||||
| 11 | | D. Thurman | 33 | 105 | 3.0 | 527 | 4 | 8 | 1 | |||||
| 12 | | D. Woodruff | 33 | 126 | 2.0 | 548 | 3 | 3 | 2 | |||||
| 13 | | K. Easley | 32 | 89 | 8.0 | 538 | 3 | 11 | 0 | |||||
| 14 | | V. McElroy | 31 | 98 | 0.0 | 296 | 1 | 9 | 0 | |||||
| 15 | | N. Cromwell | 31 | 115 | 2.0 | 531 | 4 | 13 | 0 | |||||
| 16 | | L. Breeden | 30 | 108 | 3.0 | 533 | 2 | 2 | 0 | |||||
| 17 | | M. Lee | 30 | 141 | 0.0 | 249 | 0 | 6 | 0 | |||||
| 18 | | G. Blackwood | 29 | 107 | 3.0 | 398 | 1 | 14 | 0 | |||||
| 19 | | R. James | 29 | 139 | 5.0 | 383 | 0 | 9 | 0 | |||||
| 20 | | T. Kinard | 27 | 105 | 3.0 | 574 | 2 | 6 | 0 | |||||
| 21 | | R. Clayborn | 27 | 145 | 0.0 | 427 | 1 | 7 | 0 | |||||
| 22 | | L. Hayes | 27 | 103 | 0.0 | 359 | 2 | 5 | 1 | |||||
| 23 | | D. Hicks | 27 | 97 | 1.0 | 545 | 3 | 13 | 1 | |||||
| 24 | | A. Lewis | 26 | 104 | 4.5 | 232 | 0 | 7 | 1 | |||||
| 25 | | H. Dixon | 26 | 131 | 2.0 | 225 | 0 | 4 | 0 | |||||
StatMuse has season-level data for interceptions going back to the 1940 season.
More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
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OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
