Since 2005, Charles Woodson has made the most interceptions by a defensive back, with 49 interceptions.
Interpreted as:
most career defensive int by a defensive back since 2005| NAME | INT | GP | TKL | AST | COMB | SCK | SCKY | INT YDS | INT TD | FF | FR | FR TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Woodson | 49 | 154 | 628 | 154 | 782 | 14.5 | 96.5 | 638 | 9 | 20 | 13 | 2 |
| 2 |  | A. Samuel | 48 | 128 | 332 | 34 | 366 | 0.0 | 0 | 639 | 4 | 4 | 3 | 0 |
| 3 |  | E. Reed | 43 | 126 | 340 | 72 | 412 | 2.0 | 13 | 933 | 5 | 7 | 11 | 1 |
| 4 | | D. Hall | 41 | 161 | 609 | 169 | 778 | 1.5 | 7.5 | 788 | 4 | 10 | 15 | 5 |
| 5 | | R. Nelson | 38 | 181 | 618 | 214 | 832 | 6.5 | 53.5 | 486 | 1 | 10 | 7 | 0 |
| 6 | | H. Smith | 37 | 192 | 822 | 304 | 1,126 | 20.5 | 179 | 498 | 4 | 12 | 9 | 0 |
| 7 |  | R. Sherman | 37 | 144 | 385 | 110 | 495 | 2.0 | 23 | 478 | 3 | 5 | 7 | 0 |
| 8 |  | T. Mathieu | 36 | 180 | 685 | 153 | 838 | 11.0 | 78 | 530 | 4 | 7 | 8 | 0 |
| 9 |  | P. Peterson | 36 | 201 | 571 | 81 | 652 | 4.0 | 17 | 409 | 2 | 2 | 12 | 0 |
| 10 | | D. McCourty | 35 | 205 | 740 | 231 | 971 | 3.0 | 28 | 581 | 2 | 11 | 7 | 0 |
| 11 | | A. Talib | 35 | 148 | 385 | 77 | 462 | 1.0 | 8 | 752 | 10 | 5 | 4 | 0 |
| 12 | | T. Williams | 34 | 205 | 593 | 126 | 719 | 4.5 | 29.5 | 433 | 1 | 6 | 13 | 0 |
| 13 | | T. Newman | 34 | 189 | 617 | 116 | 733 | 1.0 | 6 | 309 | 3 | 6 | 10 | 1 |
| 14 | | C. Tillman | 34 | 144 | 674 | 125 | 799 | 2.0 | 11 | 648 | 8 | 41 | 10 | 1 |
| 15 | | M. Peters | 33 | 116 | 312 | 77 | 389 | 2.0 | 22 | 897 | 7 | 12 | 10 | 1 |
| 16 | | T. Gipson Sr. | 33 | 183 | 497 | 193 | 690 | 2.5 | 13.5 | 758 | 3 | 1 | 3 | 0 |
| 17 | | B. Grimes | 33 | 148 | 500 | 73 | 573 | 0.0 | 0 | 461 | 3 | 4 | 2 | 0 |
| 18 | | J. Simmons | 32 | 134 | 479 | 187 | 666 | 4.5 | 43 | 442 | 1 | 5 | 3 | 0 |
| 19 | | S. Gilmore | 32 | 180 | 521 | 96 | 617 | 1.0 | 7 | 496 | 2 | 8 | 3 | 0 |
| 20 | | J. Joseph | 32 | 211 | 670 | 117 | 787 | 0.0 | 0 | 643 | 7 | 8 | 6 | 1 |
| 21 | | A. Cromartie | 31 | 162 | 376 | 41 | 417 | 0.0 | 0 | 545 | 3 | 2 | 5 | 2 |
| 22 | | C. Bailey | 31 | 119 | 456 | 62 | 518 | 2.0 | 14 | 340 | 3 | 5 | 1 | 0 |
| 23 | | E. Thomas | 30 | 140 | 497 | 216 | 713 | 2.0 | 12 | 455 | 2 | 11 | 6 | 1 |
| 24 | | D. Rodgers-Cromartie | 30 | 162 | 396 | 59 | 455 | 2.5 | 20.5 | 535 | 6 | 7 | 2 | 1 |
| 25 | | X. Howard | 29 | 100 | 258 | 73 | 331 | 2.0 | 11 | 254 | 2 | 4 | 5 | 2 |
StatMuse has season-level data for interceptions going back to the 1940 season.
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 Eagles | 14 | 3 | 0 | .824 |
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