Thurman Thomas has the most career rushing yards against the Patriots, with 1,925 yards.

Interpreted as:

most career rushing yards by a player vs patriots

	NAME	RUSH YDS	GP	ATT	YPC	RUSH YDS/G	RUSH TD	REC YDS	REC	TRG	AVG	REC YDS/G	REC TD
1	Thurman Thomas T. Thomas	1,925	24	419	4.6	80.2	10	494	50	4	9.9	20.6	4
2	O.J. Simpson	1,514	14	280	5.4	108.1	14	118	10		11.8	8.4	3
3	Curtis Martin C. Martin	1,218	15	311	3.9	81.2	5	221	41	54	5.4	14.7	1
4	John Riggins J. Riggins	1,108	12	236	4.7	92.3	6	91	14		6.5	7.6	0
5	Emerson Boozer E. Boozer	1,071	17	243	4.4	63.0	13	148	14		10.6	8.7	0
6	Larry Csonka L. Csonka	973	15	212	4.6	64.9	11	68	14		4.9	4.5	1
7	Edgerrin James E. James	969	10	236	4.1	96.9	3	222	33	50	6.7	22.2	2
8	Ricky Williams R. Williams	917	13	234	3.9	70.5	5	175	21	29	8.3	13.5	2
9	Johnny Hector J. Hector	868	18	209	4.2	48.2	7	187	26		7.2	10.4	0
10	Fred Jackson F. Jackson	785	14	177	4.4	56.1	5	433	40	56	10.8	30.9	1
11	Eric Dickerson E. Dickerson	758	10	224	3.4	75.8	4	209	22		9.5	20.9	1
12	Freeman McNeil F. McNeil	726	19	180	4.0	38.2	6	400	38		10.5	21.1	0
13	Lydell Mitchell L. Mitchell	725	13	205	3.5	55.8	3	314	39		8.1	24.2	0
14	LaDainian Tomlinson L. Tomlinson	716	9	144	5.0	79.6	5	190	26	40	7.3	21.1	0
15	Mercury Morris M. Morris	689	11	96	7.2	62.6	7	76	7		10.9	6.9	0
16	Joe Cribbs J. Cribbs	661	10	151	4.4	66.1	5	158	11		14.4	15.8	1
17	Randy McMillan R. McMillan	632	11	146	4.3	57.5	6	147	23		6.4	13.4	0
18	Matt Snell M. Snell	625	12	181	3.5	52.1	8	252	29		8.7	21.0	1
19	Willis McGahee W. McGahee	608	11	163	3.7	55.3	1	208	19	23	10.9	18.9	1
20	Marshall Faulk M. Faulk	603	11	166	3.6	54.8	1	496	54	16	9.2	45.1	1
21	Franco Harris F. Harris	598	8	160	3.7	74.8	5	126	12		10.5	15.8	0
22	Hoyle Granger H. Granger	595	8	134	4.4	74.4	3	198	19		10.4	24.8	0
23	Bill Mathis B. Mathis	583	20	173	3.4	29.2	5	213	22		9.7	10.7	1
24	Lamar Miller L. Miller	578	11	148	3.9	52.5	1	141	23	28	6.1	12.8	1
25	Travis Henry T. Henry	569	9	141	4.0	63.2	2	76	12	16	6.3	8.4	0

Unlock 2x data

StatMuse has game-level data for rushing yards going back to the 1960 season.

More Bills Stats

Team Leaders

PASS

3,668

Allen

RUSH

1,621

Cook

REC

719

Shakir

Team Rankings

PPG

28.3

4th

OPP PPG

21.5

12th

RUSH YDS/G

159.6

1st

PASS YDS/G

234.2

13th

2025 Division Standings

TEAM	W	L	PCT
Patriots	14	3	.824
Bills	12	5	.706
Dolphins	7	10	.412
Jets	3	14	.176

Last Game

Bills

1 - 1

Final

Broncos

1 - 0

Sat 17 Jan 2026

NFL 2025 Leaders

Pass Yards Leaders

4,707

Stafford

4,564

Goff

4,552

Prescott

Rush Yards Leaders

1,621

Cook

1,595

Henry

1,585

Taylor

Rec Yards Leaders

1,793

Smith-Njigba

1,715

Nacua

1,429

Pickens

Pass TD Leaders

46

Stafford

34

Goff

31

Maye

Rush TD Leaders

18

Taylor

16

Henry

14

Allen

Rec TD Leaders

14

Adams

11

McBride

11

St. Brown

QB Rating Leaders

113.5

Maye

109.2

Stafford

105.5

Goff

Sack Leaders

23.0

Garrett

16.5

Burns

15.0

Hunter

NFL 2025 Rankings

PPG Rankings

30.5

28.8

28.4

28.3

27.9

Opp PPG Rankings

17.2

17.4

18.3

18.8

19.1

19.3

Total Yards Rankings

394.6

391.9

379.4

376.3

373.2

369.5

Rush Yards Rankings

159.6

156.6

144.5

134.7

129.1

128.9

Pass Yards Rankings

278.5

276.9

268.6

262.3

256.1

254.0

Sack Leaders

68.0

57.0

53.0

49.0

48.0

NFL Fantasy 2025

Fantasy RB Rankings

316.3

Taylor

314.6

McCaffrey

291.8

Robinson

Fantasy WR Rankings

246

Nacua

240.9

Smith-Njigba

207

St. Brown

Fantasy TE Rankings

189.9

McBride

125.1

Goedert

122.8

Pitts

Fantasy K Rankings

202

Myers

194

Fairbairn

187.6

Aubrey

NFL 2025 Betting

Best Record ATS

15-5

12-6

14-7

12-6-1

12-7

11-7

Worst Record ATS

5-12

5-12-1

6-11

7-10

NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176