Since 2000, Jairus Byrd has the most interceptions for the Bills in a season, with 9 interceptions in his rookie season in 2009.
| NAME | INT | SEASON | TM | GP | TKL | AST | COMB | SCK | SCKY | INT YDS | INT TD | FF | FR | FR TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Byrd | 9 | 2009 | 14 | 33 | 12 | 45 | 0.0 | 0 | 118 | 0 | 0 | 0 | 0 | |
| 2 | | T. White | 6 | 2019 | 15 | 48 | 10 | 58 | 1.0 | 9 | 57 | 0 | 2 | 0 | 0 | |
| 3 | | N. Clements | 6 | 2004 | 16 | 58 | 21 | 79 | 0.5 | 0 | 77 | 1 | 5 | 2 | 0 | |
| 4 | | N. Clements | 6 | 2002 | 16 | 52 | 13 | 65 | 0.0 | 0 | 82 | 1 | 0 | 0 | 0 | |
| 5 | | M. Hyde | 5 | 2021 | 17 | 53 | 21 | 74 | 1.0 | 6 | 59 | 1 | 1 | 2 | 0 | |
| 6 | | J. Poyer | 5 | 2021 | 16 | 66 | 27 | 93 | 3.0 | 26 | 87 | 0 | 0 | 0 | 0 | |
| 7 | | M. Hyde | 5 | 2017 | 16 | 65 | 17 | 82 | 0.0 | 0 | 64 | 0 | 0 | 0 | 0 | |
| 8 | | J. Poyer | 5 | 2017 | 15 | 63 | 32 | 95 | 2.0 | 18 | 33 | 1 | 0 | 1 | 0 | |
| 9 | | S. Gilmore | 5 | 2016 | 15 | 42 | 6 | 48 | 0.0 | 0 | 135 | 0 | 0 | 0 | 0 | |
| 10 | | J. Byrd | 5 | 2012 | 16 | 53 | 23 | 76 | 0.0 | 0 | 81 | 0 | 4 | 2 | 0 | |
| 11 | | T. Spikes | 5 | 2004 | 16 | 63 | 35 | 98 | 3.0 | 16 | 122 | 2 | 3 | 1 | 0 | |
| 12 | | K. Carpenter | 5 | 2000 | 12 | 0.0 | 63 | 0 | 0 | 0 | ||||||
| 13 | | R. Douglas | 4 | 2023 | 9 | 21 | 8 | 29 | 1.0 | 10 | 58 | 1 | 0 | 2 | 0 | |
| 14 | | J. Poyer | 4 | 2022 | 12 | 44 | 19 | 63 | 0.0 | 0 | 6 | 0 | 1 | 0 | 0 | |
| 15 | | J. Poyer | 4 | 2018 | 16 | 73 | 27 | 100 | 2.0 | 15 | 11 | 0 | 1 | 1 | 0 | |
| 16 | | T. White | 4 | 2017 | 16 | 53 | 16 | 69 | 0.0 | 0 | 86 | 0 | 1 | 2 | 1 | |
| 17 | | L. McKelvin | 4 | 2014 | 10 | 45 | 3 | 48 | 0.0 | 0 | 10 | 0 | 1 | 0 | 0 | |
| 18 | | K. Alonso | 4 | 2013 | 16 | 87 | 72 | 159 | 2.0 | 17 | 38 | 0 | 1 | 2 | 0 | |
| 19 | | J. Byrd | 4 | 2013 | 11 | 37 | 11 | 48 | 1.0 | 9 | 85 | 0 | 1 | 0 | 0 | |
| 20 | | J. Leonhard | 4 | 2013 | 16 | 30 | 11 | 41 | 0.0 | 0 | 72 | 0 | 0 | 0 | 0 | |
| 21 | | A. Williams | 4 | 2013 | 14 | 60 | 22 | 82 | 0.0 | 0 | 43 | 0 | 1 | 0 | 0 | |
| 22 | | B. Scott | 4 | 2012 | 16 | 48 | 19 | 67 | 0.0 | 0 | 66 | 1 | 2 | 2 | 0 | |
| 23 | | G. Wilson | 4 | 2011 | 13 | 78 | 28 | 106 | 0.0 | 0 | 26 | 0 | 2 | 1 | 0 | |
| 24 | | G. Wilson | 4 | 2009 | 16 | 70 | 33 | 103 | 2.0 | 7 | 23 | 0 | 1 | 0 | 0 | |
| 25 | | T. McGee | 4 | 2007 | 15 | 67 | 10 | 77 | 0.0 | 0 | 4 | 0 | 0 | 0 | 0 | |
StatMuse has season-level data for interceptions going back to the 1940 season.
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More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |