Peyton Manning threw his most interceptions in a game against the San Diego Chargers on November 11, 2007, with 6 interceptions.

Interpreted as:

most passing int in a regular-season game by Peyton Manning

	NAME	INT	DATE	TM		OPP	CMP	ATT	PCT	YDS	AVG	TD	RTG	TD%	INT%	SCK	SCKY
1	Peyton Manning P. Manning	6	11/11/2007	IND	@	SD	34	56	60.7	328	5.9	2	49.4	3.6	10.7	2	17
2	Peyton Manning P. Manning	4	11/15/2015	DEN	vs	KC	5	20	25.0	35	1.8	0	0.0	0.0	20.0	2	9
3	Peyton Manning P. Manning	4	12/22/2014	DEN	@	CIN	28	44	63.6	311	7.1	2	61.8	4.5	9.1	2	11
4	Peyton Manning P. Manning	4	12/5/2010	IND	vs	DAL	36	48	75.0	365	7.6	2	75.4	4.2	8.3	0	0
5	Peyton Manning P. Manning	4	11/28/2010	IND	vs	SD	31	48	64.6	285	5.9	2	59.8	4.2	8.3	1	6
6	Peyton Manning P. Manning	4	11/25/2001	IND	vs	SF	31	51	60.8	370	7.3	1	56.8	2.0	7.8	1	6
7	Peyton Manning P. Manning	3	10/18/2015	DEN	@	CLE	26	48	54.2	290	6.0	1	53.3	2.1	6.3	0	0
8	Peyton Manning P. Manning	3	10/27/2013	DEN	vs	WAS	30	44	68.2	354	8.0	4	94.3	9.1	6.8	2	15
9	Peyton Manning P. Manning	3	9/17/2012	DEN	@	ATL	24	37	64.9	241	6.5	1	58.5	2.7	8.1	3	23
10	Peyton Manning P. Manning	3	11/21/2010	IND	@	NE	38	52	73.1	396	7.6	4	96.3	7.7	5.8	0	0
11	Peyton Manning P. Manning	3	12/13/2009	IND	vs	DEN	20	42	47.6	220	5.2	4	65.6	9.5	7.1	0	0
12	Peyton Manning P. Manning	3	12/8/2002	IND	@	TEN	26	42	61.9	297	7.1	1	61.3	2.4	7.1	1	0
13	Peyton Manning P. Manning	3	10/21/2002	IND	@	PIT	32	48	66.7	304	6.3	1	64.9	2.1	6.3	2	9
14	Peyton Manning P. Manning	3	9/15/2002	IND	vs	MIA	26	45	57.8	289	6.4	1	56.6	2.2	6.7	0	0
15	Peyton Manning P. Manning	3	12/10/2001	IND	@	MIA	19	32	59.4	173	5.4	0	35.0	0.0	9.4	1	3
16	Peyton Manning P. Manning	3	9/30/2001	IND	@	NE	20	34	58.8	196	5.8	1	48.2	2.9	8.8	2	7
17	Peyton Manning P. Manning	3	10/8/2000	IND	@	NE	31	54	57.4	334	6.2	1	58.7	1.9	5.6	2	10
18	Peyton Manning P. Manning	3	9/27/1998	IND	vs	NO	19	32	59.4	309	9.7	1	63.2	3.1	9.4	4	17
19	Peyton Manning P. Manning	3	9/13/1998	IND	@	NE	21	33	63.6	188	5.7	1	51.1	3.0	9.1	2	15
20	Peyton Manning P. Manning	3	9/6/1998	IND	vs	MIA	21	37	56.8	302	8.2	1	58.6	2.7	8.1	4	29
21	Peyton Manning P. Manning	2	11/8/2015	DEN	@	IND	21	36	58.3	281	7.8	2	78.6	5.6	5.6	1	7
22	Peyton Manning P. Manning	2	10/11/2015	DEN	@	OAK	22	35	62.9	266	7.6	0	62.3	0.0	5.7	2	12
23	Peyton Manning P. Manning	2	10/4/2015	DEN	vs	MIN	17	27	63.0	213	7.9	1	68.9	3.7	7.4	2	13
24	Peyton Manning P. Manning	2	12/7/2014	DEN	vs	BUF	14	20	70.0	173	8.7	0	56.9	0.0	10.0	0	0
25	Peyton Manning P. Manning	2	11/16/2014	DEN	@	STL	34	54	63.0	389	7.2	1	75.3	1.9	3.7	2	20

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Results may be incomplete. StatMuse has complete game-level data for intercepted passes going back to the 1950 season.

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