Bobby Layne threw the most interceptions by a quarterback in 1959, with 21 interceptions.

Regular season

	NAME	INT	SEASON	TM	GP	CMP	ATT	PCT	YDS	AVG	YDS/G	TD	RTG	TD%	INT%
1	Bobby Layne B. Layne	21	1959	PIT	12	142	297	47.8	1,986	6.7	165.5	20	62.8	6.7	7.1
2	Tobin Rote T. Rote	19	1959	DET	10	62	162	38.3	861	5.3	86.1	5	26.8	3.1	11.7
3	Billy Wade B. Wade	17	1959	LA	12	153	261	58.6	2,001	7.7	166.8	12	71.1	4.6	6.5
4	Y.A. Tittle	15	1959	SF	11	102	199	51.3	1,331	6.7	121.0	10	58.0	5.0	7.5
5	Johnny Unitas J. Unitas	14	1959	BAL	12	193	367	52.6	2,899	7.9	241.6	32	92.0	8.7	3.8
6	Norm Van Brocklin N. Van Brocklin	14	1959	PHI	12	191	340	56.2	2,617	7.7	218.1	16	79.5	4.7	4.1
7	King Hill K. Hill	13	1959	CHC	11	82	181	45.3	1,015	5.6	92.3	7	46.2	3.9	7.2
8	Ralph Guglielmi R. Guglielmi	11	1959	WAS	9	36	89	40.4	617	6.9	68.6	4	40.1	4.5	12.4
9	Eddie LeBaron E. LeBaron	11	1959	WAS	12	77	173	44.5	1,077	6.2	89.8	8	54.0	4.6	6.4
10	Ed Brown E. Brown	10	1959	CHB	12	125	247	50.6	1,881	7.6	156.8	13	76.7	5.3	4.0
11	Lamar McHan L. McHan	9	1959	GB	12	48	108	44.4	805	7.5	67.1	8	60.1	7.4	8.3
12	Milt Plum M. Plum	8	1959	CLE	12	156	266	58.6	1,992	7.5	166.0	14	87.2	5.3	3.0
13	John Brodie J. Brodie	7	1959	SF	12	30	64	46.9	354	5.5	29.5	2	35.0	3.1	10.9
14	Bart Starr B. Starr	7	1959	GB	12	70	134	52.2	972	7.3	81.0	6	69.0	4.5	5.2
15	Don Heinrich D. Heinrich	6	1959	NYG	8	22	58	37.9	329	5.7	41.1	1	23.5	1.7	10.3
16	Earl Morrall E. Morrall	6	1959	DET	12	65	137	47.4	1,102	8.0	91.8	5	69.1	3.6	4.4
17	Zeke Bratkowski Z. Bratkowski	5	1959	CHB	12	31	62	50.0	403	6.5	33.6	2	48.0	3.2	8.1
18	Charlie Conerly C. Conerly	4	1959	NYG	10	113	194	58.2	1,706	8.8	170.6	14	102.7	7.2	2.1
19	Frank Ryan F. Ryan	4	1959	LA	10	42	89	47.2	709	8.0	70.9	2	63.4	2.2	4.5
20	Jerry Reichow J. Reichow	2	1959	DET	9	9	27	33.3	168	6.2	18.7	0	24.9	0.0	7.4
21	Eagle Day E. Day	1	1959	WAS	4	6	13	46.2	79	6.1	19.8	0	33.8	0.0	7.7
22	Joe Francis J. Francis	1	1959	GB	12	5	18	27.8	91	5.1	7.6	0	25.0	0.0	5.6
23	Jim Ninowski J. Ninowski	1	1959	CLE	2	3	10	30.0	41	4.1	20.5	0	4.6	0.0	10.0
24	M.C. Reynolds	1	1959	CHC	7	19	39	48.7	329	8.4	47.0	4	101.3	10.3	2.6
25	George Shaw G. Shaw	1	1959	NYG	5	24	36	66.7	433	12.0	86.6	1	105.4	2.8	2.8

StatMuse has season-level data for intercepted passes going back to the 1932 season.

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DATE	MATCHUP			TIME (ET)
Sun 9/20	PIT	@	NE	1:00 PM
Sun 9/27	CIN	@	PIT	1:00 PM
Thu 10/1	PIT	@	CLE	8:15 PM
Sun 10/11	IND	@	PIT	1:00 PM
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Lions	1	0	0	1.000
Packers	0	1	0	.000
NFC South	W	L	T	PCT
Falcons	0	1	0	.000
Buccaneers	0	1	0	.000
Saints	0	1	0	.000
Panthers	0	1	0	.000
NFC West	W	L	T	PCT
49ers	1	0	0	1.000
Cardinals	1	0	0	1.000
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AFC East	W	L	T	PCT
Jets	1	0	0	1.000
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Ravens	1	0	0	1.000
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Steelers	1	0	0	1.000
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AFC South	W	L	T	PCT
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Texans	0	1	0	.000
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Colts	0	1	0	.000
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Chargers	0	1	0	.000
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Thu 9/10	SF	@	LAR	27-7
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Sun 9/13	ATL	@	PIT	13-20

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DATE	MATCHUP			TIME (ET)
Thu 9/17	DET	@	BUF	8:15 PM
Sun 9/20	PHI	@	TEN	1:00 PM
Sun 9/20	PIT	@	NE	1:00 PM
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Bobby Layne threw the most interceptions by a quarterback in 1959, with 21 interceptions.

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