The San Francisco 49ers had the most tackles for loss per game played by a team in 2021, with 5.76.

most tfl per game by a team this season
202149ers2021Steelers2021Bills2021Saints2021Rams2021Panthers2021Buccaneers2021Texans2021Bengals2021Bears2021Cardinals2021Browns2021Ravens2021Dolphins2021Cowboys2021Eagles2021Jets2021Seahawks2021Titans2021Broncos2021Raiders2021Chargers5.765.535.415.1854.944.764.764.714.534.474.474.474.354.244.184.184.124.063.823.823.82
TEAMSEASONGPTFL/GPTFLTKLASTCOMBSCKSCKYINTINT YDSINT TDFFFRFR TD
San Francisco 49ersSan Francisco 49ers2021175.76987054111,11648.03649136222110
Pittsburgh SteelersPittsburgh Steelers2021175.53947904061,19655.03211310501890
Buffalo BillsBuffalo Bills2021175.41927003181,01842.027619238112110
New Orleans SaintsNew Orleans Saints2021175.18887153761,09146.03101931321370
Los Angeles RamsLos Angeles Rams2021175857474441,19150.03671919201560
Carolina PanthersCarolina Panthers2021174.94846934041,09739.0293910301470
Tampa Bay BuccaneersTampa Bay Buccaneers2021174.76817363161,05247.028517177216120
Houston TexansHouston Texans2021174.76817634371,20032.02251729511680
Cincinnati BengalsCincinnati Bengals2021174.71807204111,13142.02761326611781
Chicago BearsChicago Bears2021174.53777083851,09349.0366813511481
Arizona CardinalsArizona Cardinals2021174.47767043581,06241.022713247121141
Cleveland BrownsCleveland Browns2021174.47767043981,10243.02731314811261
Baltimore RavensBaltimore Ravens2021174.47766823701,05234.02449381861
Miami DolphinsMiami Dolphins2021174.35746994031,10248.038014175314122
Dallas CowboysDallas Cowboys2021174.24726873331,02041.02972640551381
Philadelphia EaglesPhiladelphia Eagles2021174.18716725071,17929.02201213821343
New York JetsNew York Jets2021174.18717704481,21833.0273711411370
Seattle SeahawksSeattle Seahawks2021174.12708335041,33734.025311920970
Tennessee TitansTennessee Titans2021174.06697073501,05743.03161612821362
Denver BroncosDenver Broncos2021173.82656413811,02236.0249132211660
Las Vegas RaidersLas Vegas Raiders2021173.82657134531,16635.020766501390
Los Angeles ChargersLos Angeles Chargers2021173.82657424271,16935.02311170019101
Jacksonville JaguarsJacksonville Jaguars2021173.71637274261,15332.02367570821
Minnesota VikingsMinnesota Vikings2021173.59617644431,20751.03781625621380
Washington Football TeamWashington Football Team2021173.53606984171,11538.0187111202980
New England PatriotsNew England Patriots2021173.53607224021,12436.02562332231170
Detroit LionsDetroit Lions2021173.41587334301,16330.02011110801080
Atlanta FalconsAtlanta Falcons2021173.41587294811,21018.01521220221480
Indianapolis ColtsIndianapolis Colts2021173.29567663361,10233.022319175018141
Kansas City ChiefsKansas City Chiefs2021173.29566903681,05831.020915160218142
New York GiantsNew York Giants2021173.12537275441,27134.02051513511270
Green Bay PackersGreen Bay Packers2021173.06527112951,00639.02971816421080
StatMuse has team, season-level data for tackles for loss going back to the 2001 season.