Eli Manning had his most passing touchdowns in a game against the Saints on November 1, 2015, with 6 touchdowns.

Interpreted as:

most passing touchdowns in a regular-season game from Eli Manning

	NAME	TD	DATE	TM		OPP	CMP	ATT	PCT	YDS	AVG	INT	RTG	TD%	INT%	SCK	SCKY
1	Eli Manning E. Manning	6	11/1/2015	NYG	@	NO	30	41	73.2	350	8.5	0	138.2	14.6	0.0	3	21
2	Eli Manning E. Manning	5	12/30/2012	NYG	vs	PHI	13	21	61.9	208	9.9	0	134.5	23.8	0.0	1	11
3	Eli Manning E. Manning	4	11/6/2016	NYG	vs	PHI	22	36	61.1	257	7.1	2	96.6	11.1	5.6	1	9
4	Eli Manning E. Manning	4	12/20/2015	NYG	vs	CAR	29	46	63.0	245	5.3	1	96.7	8.7	2.2	0	0
5	Eli Manning E. Manning	4	12/14/2015	NYG	@	MIA	27	31	87.1	337	10.9	0	151.5	12.9	0.0	0	0
6	Eli Manning E. Manning	4	9/25/2014	NYG	@	WAS	28	39	71.8	300	7.7	1	117.5	10.3	2.6	1	5
7	Eli Manning E. Manning	4	9/8/2013	NYG	@	DAL	27	42	64.3	450	10.7	3	102.3	9.5	7.1	3	22
8	Eli Manning E. Manning	4	12/9/2012	NYG	vs	NO	22	35	62.9	259	7.4	2	99.6	11.4	5.7	0	0
9	Eli Manning E. Manning	4	9/25/2011	NYG	@	PHI	16	23	69.6	254	11.0	0	145.7	17.4	0.0	3	22
10	Eli Manning E. Manning	4	12/19/2010	NYG	vs	PHI	23	39	59.0	289	7.4	1	105.6	10.3	2.6	2	25
11	Eli Manning E. Manning	4	10/25/2010	NYG	@	DAL	25	35	71.4	306	8.7	3	100.4	11.4	8.6	1	9
12	Eli Manning E. Manning	4	12/29/2007	NYG	vs	NE	22	32	68.8	251	7.8	1	118.6	12.5	3.1	1	14
13	Eli Manning E. Manning	4	9/9/2007	NYG	@	DAL	28	41	68.3	312	7.6	1	113.1	9.8	2.4	1	5
14	Eli Manning E. Manning	4	10/2/2005	NYG	vs	STL	19	35	54.3	296	8.5	0	120.7	11.4	0.0	1	4
15	Eli Manning E. Manning	3	12/9/2018	NYG	@	WAS	14	22	63.6	197	9.0	0	132.0	13.6	0.0	2	22
16	Eli Manning E. Manning	3	11/12/2018	NYG	@	SF	19	31	61.3	188	6.1	0	110.7	9.7	0.0	1	8
17	Eli Manning E. Manning	3	12/17/2017	NYG	vs	PHI	37	57	64.9	434	7.6	1	98.1	5.3	1.8	1	5
18	Eli Manning E. Manning	3	9/24/2017	NYG	@	PHI	35	47	74.5	366	7.8	2	100.1	6.4	4.3	0	0
19	Eli Manning E. Manning	3	11/27/2016	NYG	@	CLE	15	27	55.6	194	7.2	0	115.4	11.1	0.0	1	2
20	Eli Manning E. Manning	3	11/14/2016	NYG	vs	CIN	28	44	63.6	240	5.5	2	81.6	6.8	4.5	1	11
21	Eli Manning E. Manning	3	10/16/2016	NYG	vs	BAL	32	46	69.6	403	8.8	2	100.2	6.5	4.3	1	6
22	Eli Manning E. Manning	3	9/11/2016	NYG	@	DAL	19	28	67.9	207	7.4	1	110.3	10.7	3.6	2	4
23	Eli Manning E. Manning	3	10/11/2015	NYG	vs	SF	41	54	75.9	441	8.2	1	110.2	5.6	1.9	0	0
24	Eli Manning E. Manning	3	10/4/2015	NYG	@	BUF	20	35	57.1	212	6.1	1	91.6	8.6	2.9	1	1
25	Eli Manning E. Manning	3	12/21/2014	NYG	@	STL	25	32	78.1	391	12.2	0	148.8	9.4	0.0	1	5

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Results may be incomplete. StatMuse has complete game-level data for passing touchdowns going back to the 1950 season.

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DATE	MATCHUP			TIME (ET)
Thu 10/9	PHI	@	NYG	8:15 PM
Sun 10/19	NYG	@	DEN	4:05 PM
Sun 10/26	NYG	@	PHI	1:00 PM
Sun 11/2	SF	@	NYG	1:00 PM
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Packers	2	1	1	.625
NFC South	W	L	T	PCT
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Falcons	2	2	0	.500
NFC West	W	L	T	PCT
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Seahawks	3	2	0	.600

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Patriots	3	2	0	.600
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Bengals	2	3	0	.400
AFC South	W	L	T	PCT
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DATE	MATCHUP			SCORE
Wed 9/3	DAL	@	PHI	20-24
Thu 9/4	KC	@	LAC	21-27
Sat 9/6	PIT	@	NYJ	34-32
Sat 9/6	TB	@	ATL	23-20
Sat 9/6	LV	@	NE	20-13

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DATE	MATCHUP			TIME (ET)
Mon 10/6	KC	@	JAX	8:15 PM
Thu 10/9	PHI	@	NYG	8:15 PM
Sun 10/12	DEN	@	NYJ	9:30 AM
Sun 10/12	ARI	@	IND	1:00 PM
Sun 10/12	LAR	@	BAL	1:00 PM

Eli Manning had his most passing touchdowns in a game against the Saints on November 1, 2015, with 6 touchdowns.

Interpreted as:

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