nfl players with the most rushing yards in the afc in 2025

James Cook III rushed for the most yards in the AFC in 2025, with 1,621 yards.

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Regular season

	NAME	RUSH YDS	SEASON	TM	GP	ATT	YPC	RUSH YDS/G	RUSH TD	REC YDS	REC	TRG	AVG	REC YDS/G	REC TD
1	James Cook III J. Cook III	1,621	2025	BUF	17	309	5.2	95.4	12	291	33	40	8.8	17.1	2
2	Derrick Henry D. Henry	1,595	2025	BAL	17	307	5.2	93.8	16	150	15	21	10.0	8.8	0
3	Jonathan Taylor J. Taylor	1,585	2025	IND	17	323	4.9	93.2	18	378	46	55	8.2	22.2	2
4	De'Von Achane D. Achane	1,350	2025	MIA	16	238	5.7	84.4	8	488	67	85	7.3	30.5	4
5	Travis Etienne Jr. T. Etienne Jr.	1,107	2025	JAX	17	260	4.3	65.1	7	292	36	52	8.1	17.2	6
6	Tony Pollard T. Pollard	1,082	2025	TEN	17	242	4.5	63.6	5	206	33	41	6.2	12.1	0
7	Breece Hall B. Hall	1,065	2025	NYJ	16	243	4.4	66.6	4	350	36	48	9.7	21.9	1
8	Chase Brown C. Brown	1,019	2025	CIN	17	232	4.4	59.9	6	437	69	88	6.3	25.7	5
9	Ashton Jeanty A. Jeanty	975	2025	LV	17	266	3.7	57.4	5	346	55	73	6.3	20.4	5
10	Jaylen Warren J. Warren	958	2025	PIT	16	211	4.5	59.9	6	333	40	45	8.3	20.8	2
11	TreVeyon Henderson T. Henderson	911	2025	NE	17	180	5.1	53.6	9	221	35	42	6.3	13.0	1
12	Quinshon Judkins Q. Judkins	827	2025	CLE	14	230	3.6	59.1	7	171	26	36	6.6	12.2	0
13	J.K. Dobbins	772	2025	DEN	10	153	5.0	77.2	4	37	11	14	3.4	3.7	0
14	Woody Marks W. Marks	703	2025	HOU	16	196	3.6	43.9	2	208	24	36	8.7	13.0	3
15	Kimani Vidal K. Vidal	643	2025	LAC	13	155	4.1	49.5	3	136	16	22	8.5	10.5	1
16	Kareem Hunt K. Hunt	611	2025	KC	17	163	3.7	35.9	8	143	18	25	7.9	8.4	1
17	Rhamondre Stevenson R. Stevenson	603	2025	NE	14	130	4.6	43.1	7	345	32	37	10.8	24.6	2
18	Josh Allen J. Allen	579	2025	BUF	17	112	5.2	34.1	14	0	0	0		0.0	0
19	Omarion Hampton O. Hampton	545	2025	LAC	9	124	4.4	60.6	4	192	32	35	6.0	21.3	1
20	RJ Harvey	540	2025	DEN	17	146	3.7	31.8	7	356	47	58	7.6	20.9	5
21	Kenny Gainwell K. Gainwell	537	2025	PIT	17	114	4.7	31.6	5	486	73	85	6.7	28.6	3
22	Nick Chubb N. Chubb	506	2025	HOU	15	122	4.1	33.7	3	67	13	20	5.2	4.5	0
23	Justin Herbert J. Herbert	498	2025	LAC	16	83	6.0	31.1	2	0	0	0		0.0	0
24	Isiah Pacheco I. Pacheco	462	2025	KC	13	118	3.9	35.5	1	101	19	26	5.3	7.8	1
25	Drake Maye D. Maye	450	2025	NE	17	103	4.4	26.5	4	2	1	1	2.0	0.1	0

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StatMuse has season-level data for rushing yards going back to the 1932 season.

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More Bills Stats

Team Leaders

PASS

786

Allen

RUSH

346

Cook

REC

263

Kincaid

Team Rankings

PPG

33.7

1st

OPP PPG

26.0

21st

RUSH YDS/G

155.0

4th

PASS YDS/G

262.0

10th

2026 Division Standings

TEAM	W	L	PCT
Bills	3	0	1.000
Patriots	1	2	.333
Jets	1	2	.333
Dolphins	0	3	.000

Schedule

DATE	MATCHUP			TIME (ET)
Sun 10/4	NE	@	BUF	1:00 PM
Mon 10/12	BUF	@	LAR	8:15 PM
Sun 10/18	BUF	@	LV	4:25 PM
Sun 11/1	BAL	@	BUF	1:00 PM
Mon 11/9	BUF	@	MIN	8:15 PM

Last Game

Chargers

0 - 3

Final

Bills

3 - 0

Sun 27 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

999

Rodgers

939

Young

917

Shough

Rush Yards Leaders

360

Walker

349

Robinson

346

Cook

Rec Yards Leaders

405

Smith-Njigba

375

Olave

358

Adams

Pass TD Leaders

9

Purdy

9

Cousins

8

Shough

Rush TD Leaders

6

Allen

6

Henry

4

Gibbs

Rec TD Leaders

6

Smith-Njigba

5

St. Brown

4

Watson

QB Rating Leaders

133.1

Purdy

127.3

Lock

116.1

Goff

Sack Leaders

6.0

Rousseau

4.5

Watt

4.0

Anderson

NFL 2026 Rankings

PPG Rankings

33.7

32.7

31.0

30.7

29.7

Opp PPG Rankings

12.0

13.7

16.7

17.0

Total Yards Rankings

417.7

416.3

408.0

401.7

399.3

398.7

Rush Yards Rankings

184.3

173.0

167.3

155.0

153.3

136.3

Pass Yards Rankings

313.0

305.7

295.0

281.3

276.0

270.7

Sack Leaders

14.0

12.0

11.0

10.0

NFL Fantasy 2026

Fantasy RB Rankings

80.3

Gibbs

69.9

Henry

68.2

Walker

Fantasy WR Rankings

77.1

Smith-Njigba

52.8

St. Brown

52.4

Watson

Fantasy TE Rankings

35.4

Kittle

35.1

Kelce

33.3

Fannin

Fantasy K Rankings

42

McPherson

39

McLaughlin

38

Shrader

NFL 2026 Betting

Best Record ATS

3-0

2-0-1

3-1

2-1

Worst Record ATS

0-3

NFL 2026 Standings

NFC East	W	L	T	PCT
Eagles	2	1	0	.667
Giants	2	1	0	.667
Cowboys	1	2	0	.333
Commanders	1	2	0	.333
NFC North	W	L	T	PCT
Vikings	3	0	0	1.000
Lions	2	1	0	.667
Bears	2	1	0	.667
Packers	1	2	0	.333
NFC South	W	L	T	PCT
Panthers	1	2	0	.333
Saints	1	2	0	.333
Falcons	1	2	0	.333
Buccaneers	0	3	0	.000
NFC West	W	L	T	PCT
49ers	3	0	0	1.000
Seahawks	2	1	0	.667
Rams	1	2	0	.333
Cardinals	1	2	0	.333

AFC East	W	L	T	PCT
Bills	3	0	0	1.000
Jets	1	2	0	.333
Patriots	1	2	0	.333
Dolphins	0	3	0	.000
AFC North	W	L	T	PCT
Browns	3	1	0	.750
Ravens	2	1	0	.667
Bengals	2	1	0	.667
Steelers	2	2	0	.500
AFC South	W	L	T	PCT
Jaguars	2	1	0	.667
Colts	1	2	0	.333
Titans	0	3	0	.000
Texans	0	3	0	.000
AFC West	W	L	T	PCT
Chiefs	3	0	0	1.000
Raiders	3	0	0	1.000
Broncos	2	1	0	.667
Chargers	0	3	0	.000

NFL 2026 Scores & Schedule

Scores

DATE	MATCHUP			SCORE
Wed 9/9	NE	@	SEA	10-13
Thu 9/10	SF	@	LAR	27-7
Sun 9/13	CHI	@	CAR	59-37
Sun 9/13	BAL	@	IND	41-23
Sun 9/13	ATL	@	PIT	13-20

Schedule

DATE	MATCHUP			TIME (ET)
Sun 10/4	IND	@	WAS	9:30 AM
Sun 10/4	ARI	@	NYG	1:00 PM
Sun 10/4	NE	@	BUF	1:00 PM
Sun 10/4	NYJ	@	CHI	1:00 PM
Sun 10/4	DAL	@	HOU	1:00 PM

James Cook III rushed for the most yards in the AFC in 2025, with 1,621 yards.

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More Bills Stats

786

346

263

NFL 2026 Leaders

999

939

917

360

349

346

405

375

358

9

9

8

6

6

4

6

5

4

133.1

127.3

116.1

6.0

4.5

4.0

NFL 2026 Rankings

NFL Fantasy 2026

80.3

69.9

68.2

77.1

52.8

52.4

35.4

35.1

33.3

42

39

38

NFL 2026 Betting

NFL 2026 Standings

NFL 2026 Scores & Schedule

Scores

Schedule