O.J. Simpson gained his most all-purpose yards in a game against the Jets on October 4, 1970, with 303 yards.
Interpreted as:
O.J. Simpson most total yards in a regular-season game| NAME | YDS | DATE | TM | OPP | RUSH YDS | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | O.J. Simpson | 303 | 10/4/1970 | vs | 99 | 21 | 4.7 | 1 | 63 | 3 | 21.0 | 0 | |||
| 2 | | O.J. Simpson | 273 | 11/25/1976 | @ | 273 | 29 | 9.4 | 2 | 0 | 0 | 0 | ||||
| 3 | | O.J. Simpson | 250 | 9/16/1973 | @ | 250 | 29 | 8.6 | 2 | 0 | 0 | 0 | ||||
| 4 | | O.J. Simpson | 227 | 9/28/1975 | @ | 227 | 28 | 8.1 | 1 | 0 | 0 | 0 | ||||
| 5 | | O.J. Simpson | 226 | 11/16/1969 | vs | 72 | 21 | 3.4 | 0 | 81 | 3 | 27.0 | 2 | |||
| 6 | | O.J. Simpson | 219 | 12/9/1973 | vs | 219 | 22 | 10.0 | 1 | 0 | 0 | 0 | ||||
| 7 | | O.J. Simpson | 218 | 11/17/1975 | @ | 197 | 17 | 11.6 | 2 | 21 | 2 | 10.5 | 0 | |||
| 8 | | O.J. Simpson | 215 | 12/5/1976 | @ | 203 | 24 | 8.5 | 1 | 12 | 2 | 6.0 | 0 | |||
| 9 | | O.J. Simpson | 213 | 12/14/1975 | @ | 185 | 21 | 8.8 | 1 | 28 | 2 | 14.0 | 0 | |||
| 10 | | O.J. Simpson | 213 | 12/7/1975 | @ | 96 | 18 | 5.3 | 1 | 117 | 8 | 14.6 | 1 | |||
| 11 | | O.J. Simpson | 204 | 10/7/1973 | vs | 171 | 27 | 6.3 | 1 | 33 | 3 | 11.0 | 0 | |||
| 12 | | O.J. Simpson | 200 | 12/16/1973 | @ | 200 | 34 | 5.9 | 1 | 0 | 0 | 0 | ||||
| 13 | | O.J. Simpson | 196 | 10/29/1972 | vs | 189 | 22 | 8.6 | 1 | 7 | 3 | 2.3 | 0 | |||
| 14 | | O.J. Simpson | 194 | 11/9/1975 | vs | 123 | 19 | 6.5 | 1 | 71 | 3 | 23.7 | 2 | |||
| 15 | | O.J. Simpson | 189 | 12/12/1976 | @ | 171 | 28 | 6.1 | 1 | 18 | 1 | 18.0 | 0 | |||
| 16 | | O.J. Simpson | 178 | 9/21/1975 | vs | 173 | 32 | 5.4 | 2 | 5 | 1 | 5.0 | 0 | |||
| 17 | | O.J. Simpson | 173 | 10/12/1975 | @ | 159 | 32 | 5.0 | 1 | 14 | 1 | 14.0 | 0 | |||
| 18 | | O.J. Simpson | 172 | 9/28/1969 | vs | 110 | 24 | 4.6 | 0 | 45 | 5 | 9.0 | 1 | |||
| 19 | | O.J. Simpson | 167 | 9/14/1969 | vs | 35 | 10 | 3.5 | 1 | 64 | 2 | 32.0 | 0 | |||
| 20 | | O.J. Simpson | 166 | 10/31/1976 | vs | 166 | 29 | 5.7 | 0 | 0 | 0 | 0 | ||||
| 21 | | O.J. Simpson | 166 | 10/14/1973 | vs | 166 | 22 | 7.5 | 2 | 0 | 0 | 0 | ||||
| 22 |  | O.J. Simpson | 164 | 9/10/1978 | vs | 108 | 27 | 4.0 | 0 | 56 | 5 | 11.2 | 1 | |||
| 23 | | O.J. Simpson | 160 | 11/2/1975 | @ | 94 | 21 | 4.5 | 0 | 66 | 2 | 33.0 | 1 | |||
| 24 | | O.J. Simpson | 159 | 11/2/1969 | vs | 41 | 16 | 2.6 | 0 | 32 | 2 | 16.0 | 0 | |||
| 25 | | O.J. Simpson | 158 | 9/24/1972 | vs | 138 | 29 | 4.8 | 0 | 20 | 2 | 10.0 | 0 | |||
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| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |