The San Francisco 49ers couldn't pull it off against the Denver Broncos, 11 to 10, on September 25, 2022. With the loss, the 49ers moved to 1-2 on the season.
| TEAM | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 9/25/2022 | @ | L 10-11 | 1 | 13 | 267 | 261 | 10.0 | |||
| 2 | | 49ers | 12/9/2018 | vs | W 20-14 | 2 | 24 | 389 | 274 | 30.8 | 0.0 | ||
| 3 | | 49ers | 10/19/2014 | @ | L 17-42 | 2 | 22 | 310 | 419 | 23.1 | 50.0 | ||
| 4 | | 49ers | 10/31/2010 | vs | W 24-16 | 3 | 16 | 339 | 398 | 38.5 | |||
| 5 | | 49ers | 12/31/2006 | @ | W 26-23 | 2 | 17 | 360 | 325 | 45.0 | 50.0 | ||
| 6 | | 49ers | 9/15/2002 | vs | L 14-24 | 2 | 18 | 261 | 299 | 61.5 | |||
| 7 | | 49ers | 12/23/2000 | @ | L 9-38 | 1 | 16 | 192 | 362 | 28.6 | 66.7 | ||
| 8 | | 49ers | 12/15/1997 | vs | W 34-17 | 4 | 18 | 323 | 237 | 38.5 | |||
| 9 | | 49ers | 12/17/1994 | vs | W 42-19 | 6 | 25 | 488 | 334 | 66.7 | 100.0 | ||
| 10 | | 49ers | 1/28/1990 | @ | W 55-10 | 8 | 28 | 461 | 167 | ||||
| 11 | | 49ers | 10/9/1988 | vs | L 13-16 | 1 | 21 | 417 | 314 | ||||
| 12 | | 49ers | 11/11/1985 | @ | L 16-17 | 1 | 16 | 341 | 336 | ||||
| 13 | | 49ers | 9/19/1982 | @ | L 21-24 | 3 | 20 | 413 | 283 | ||||
| 14 | | 49ers | 11/18/1979 | vs | L 28-38 | 4 | 18 | 240 | 369 | ||||
| 15 | | 49ers | 9/23/1973 | @ | W 36-34 | 3 | 16 | 347 | 355 | ||||
| 16 | | 49ers | 10/25/1970 | vs | W 19-14 | 1 | 16 | 362 | 283 |
More 49ers Stats
Team Leaders 
PASS
262
Purdy
RUSH
48
McCaffrey
REC
111
Robinson
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
