Trevor Lawrence had his most interceptions in a game against the Titans on December 12, 2021, with 4 interceptions.

Interpreted as:

trevor most passing interceptions in a regular-season game

	NAME	INT	DATE	TM		OPP	CMP	ATT	PCT	YDS	AVG	TD	RTG	TD%	INT%	SCK	SCKY
1	Trevor Lawrence T. Lawrence	4	12/12/2021	JAX	@	TEN	24	40	60.0	221	5.5	0	35.5	0.0	10.0	3	37
2	Trevor Lawrence T. Lawrence	3	11/23/2025	JAX	@	ARI	18	30	60.0	256	8.5	3	81.4	10.0	10.0	3	19
3	Trevor Lawrence T. Lawrence	3	12/10/2023	JAX	@	CLE	28	50	56.0	257	5.1	3	65.2	6.0	6.0	4	22
4	Trevor Lawrence T. Lawrence	3	1/2/2022	JAX	@	NE	17	27	63.0	193	7.1	1	57.1	3.7	11.1	2	20
5	Trevor Lawrence T. Lawrence	3	9/12/2021	JAX	@	HOU	28	51	54.9	332	6.5	3	70.1	5.9	5.9	1	13
6	Trevor Siemian T. Siemian	3	12/3/2017	DEN	@	MIA	19	41	46.3	200	4.9	0	30.5	0.0	7.3	3	33
7	Trevor Siemian T. Siemian	3	10/30/2017	DEN	@	KC	19	36	52.8	198	5.5	1	43.5	2.8	8.3	3	11
8	Trevor Lawrence T. Lawrence	2	9/14/2025	JAX	@	CIN	24	42	57.1	271	6.5	3	80.6	7.1	4.8	1	10
9	Trevor Lawrence T. Lawrence	2	11/3/2024	JAX	@	PHI	16	31	51.6	169	5.5	0	40.9	0.0	6.5	2	14
10	Trevor Lawrence T. Lawrence	2	1/7/2024	JAX	@	TEN	29	43	67.4	280	6.5	2	81.5	4.7	4.7	0	0
11	Trevor Lawrence T. Lawrence	2	12/24/2023	JAX	@	TB	17	29	58.6	211	7.3	1	64.0	3.4	6.9	3	28
12	Trevor Siemian T. Siemian	2	12/17/2023	NYJ	@	MIA	14	26	53.8	110	4.2	0	32.5	0.0	7.7	2	19
13	Trevor Lawrence T. Lawrence	2	11/12/2023	JAX	vs	SF	17	29	58.6	185	6.4	0	48.8	0.0	6.9	5	28
14	Trevor Lawrence T. Lawrence	2	10/30/2022	JAX	vs	DEN	18	31	58.1	133	4.3	1	52.2	3.2	6.5	2	19
15	Trevor Lawrence T. Lawrence	2	10/9/2022	JAX	vs	HOU	25	47	53.2	286	6.1	0	54.0	0.0	4.3	0	0
16	Trevor Siemian T. Siemian	2	11/21/2021	NO	@	PHI	22	40	55.0	214	5.4	3	74.4	7.5	5.0	0	0
17	Trevor Lawrence T. Lawrence	2	9/26/2021	JAX	vs	ARI	22	34	64.7	219	6.4	1	68.1	2.9	5.9	3	17
18	Trevor Lawrence T. Lawrence	2	9/19/2021	JAX	vs	DEN	14	33	42.4	118	3.6	1	37.2	3.0	6.1	1	4
19	Trevor Siemian T. Siemian	2	10/15/2017	DEN	vs	NYG	29	50	58.0	376	7.5	1	71.8	2.0	4.0	4	28
20	Trevor Siemian T. Siemian	2	9/24/2017	DEN	@	BUF	24	40	60.0	259	6.5	0	58.2	0.0	5.0	3	4
21	Trevor Siemian T. Siemian	2	11/13/2016	DEN	@	NO	25	40	62.5	258	6.5	2	76.9	5.0	5.0	6	24
22	Trevor Siemian T. Siemian	2	9/8/2016	DEN	vs	CAR	18	26	69.2	178	6.8	1	69.1	3.8	7.7	2	19
23	Trevor Lawrence T. Lawrence	1	12/28/2025	JAX	@	IND	23	37	62.2	263	7.1	0	72.2	0.0	2.7	2	14
24	Trevor Lawrence T. Lawrence	1	11/16/2025	JAX	vs	LAC	14	22	63.6	153	7.0	1	80.3	4.5	4.5	0	0
25	Trevor Lawrence T. Lawrence	1	11/9/2025	JAX	@	HOU	13	23	56.5	158	6.9	1	74.2	4.3	4.3	5	39

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Results may be incomplete. StatMuse has complete game-level data for intercepted passes going back to the 1950 season.

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Jets - e	3	14	0	.176
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Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
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Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
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