Donovan McNabb scored his most rushing touchdowns in a game against the Packers on October 2, 2006, with 2 touchdowns.

what are the most rushing tds in a game by donovan mcnabb
Interpreted as:
What are the most rushing tds in a regular-season game by Donovan McNabb?
10/2/2006McNabb10/9/2011McNabb12/20/2009McNabb9/13/2009McNabb12/28/2008McNabb10/26/2008McNabb10/8/2006McNabb11/14/2005McNabb11/28/2004McNabb9/26/2004McNabb9/20/2004McNabb12/27/2003McNabb12/15/2003McNabb11/10/2003McNabb11/3/2002McNabb10/28/2002McNabb10/20/2002McNabb10/6/2002McNabb9/22/2002McNabb9/16/2002McNabb11/11/2001McNabb9/23/2001McNabb12/3/2000McNabb21111111111111111111111
Results may be incomplete. StatMuse has complete game-level data for rushing touchdowns going back to the 1960 season.

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