Lionel Vital has averaged the most career rushing yards per game by a running back, with 115.3 per game.

what running back has the most rushing yards per game
VitalBrownSandersDavisDickersonElliottPaytonPortisCookSimsMartinWillhiteSimpsonJamesPetersonCampbellFosterSmithLewisChubbTomlinsonWilliams115.3104.399.897.590.889.988.087.885.185.183.983.783.282.782.381.881.681.281.080.880.579.9
NAMEGPRUSH YDS/GRUSH YDSATTRUSH AVGRUSH TDREC YDSRECTRGREC AVGREC YDS/GREC TD
Lionel VitalLionel Vital3115.3346804.3213113.04.30
Jim BrownJim Brown118104.312,3122,3595.21062,4992629.521.220
Barry SandersBarry Sanders15399.815,2693,0625.0992,9213528.319.110
Terrell DavisTerrell Davis7897.57,6071,6554.6601,280169267.616.45
Eric DickersonEric Dickerson14690.813,2592,9964.4902,1372817.614.66
Ezekiel ElliottEzekiel Elliott7189.96,3841,4134.5461,9572413158.127.610
Walter PaytonWalter Payton19088.016,7263,8384.41104,5384929.223.915
Clinton PortisClinton Portis11387.89,9232,2304.4752,0182473388.217.95
Dalvin CookDalvin Cook4385.13,6617694.8331,2751481828.629.73
Billy SimsBilly Sims6085.15,1061,1314.5422,07218611.134.55
Curtis MartinCurtis Martin16883.914,1013,5184.0903,3294844096.919.810
Kevin WillhiteKevin Willhite383.7251534.703766.212.30
O.J. SimpsonO.J. Simpson13583.211,2362,4044.7612,14220310.615.914
Edgerrin JamesEdgerrin James14882.712,2463,0284.0803,3644335847.822.711
Adrian PetersonAdrian Peterson18082.314,8203,1924.61182,4663014198.213.76
Earl CampbellEarl Campbell11581.89,4072,1874.3748061216.77.00
Arian FosterArian Foster8081.66,5271,4764.4542,3462553559.229.314
Emmitt SmithEmmitt Smith22681.218,3554,4094.21643,2245151306.314.311
Jamal LewisJamal Lewis13181.010,6072,5424.2581,8792212988.514.34
Nick ChubbNick Chubb4480.83,5576805.22857772968.013.12
LaDainian TomlinsonLaDainian Tomlinson17080.513,6843,1744.31454,7726248687.628.117
Domanick WilliamsDomanick Williams4079.93,1957704.1231,2761542008.331.95
Josh JacobsJosh Jacobs2879.12,2155154.31940453727.614.40
George RogersGeorge Rogers9278.07,1761,6924.254368556.74.00
Jonathan TaylorJonathan Taylor1577.91,1692325.01129936398.319.91
StatMuse has season-level data for rushing yards per game going back to the 1932 season.

See Trending NFL Searches